Excited to share our latest work with an amazing team, Walter Chazin Alex Blee and Zachary Nagel lab, on improving tumor #VUS interpretation with an active learning strategy: biorxiv.org/content/10.110…

Excited to share new preprint on work done by Sarah Fong (Sarah Fong) exploring the evolution of human enhancers with multiple sequence ancestors and relationships to gene regulatory function and selection pressures. doi.org/10.1101/2022.0…

Nice new work by Evonne McArthur Capra Lab and colleagues further probing changes in gene regulation between us and our closest extinct relatives (Neanderthals/Denisovans): biorxiv.org/content/10.110…

Brilliant new preprint from the Capra Lab and the Pollard lab on the 3D genome organization of a Denisovan and three Neanderthals. Well done Evonne McArthur and the rest of the team! biorxiv.org/content/10.110…

What? 3D chromatin organization in Neandertal and Denisovan genomes! From my Gladstone Institutes and UC San Francisco colleagues in Tony Capra Capra Lab and Katie Pollard's labs! biorxiv.org/content/10.110…

Check out our preprint and Evonne McArthur's thread below. We apply deep learning to reconstruct Neanderthal and Denisovan 3D folding patterns and then ask some cool questions about how this might have affected recent human evolution! biorxiv.org/content/10.110…

Experiencing a rollercoaster of emotions since defending my PhD. But these faces capture the best one, pure JOY!!🤗🍾I could not have asked for a better mentor than Tony Capra Lab. The entire journey was amazing and the few extra letters after my name don't hurt either🙃🎓

Check out our lab manuscript template for some tricks, tips, and preferences (in both LaTeX and MS Word). Hoping it can be helpful to others! 🗒️✍️

Check out this thread on new work lead by Abin Abraham and The Lab LaBella from the RokasLab to quantify evolutionary signatures on genomic regions associated with traits from hundreds of GWAS. And Abin Abraham has put together a package if you want to try it out yourself!

We are very excited to share our newest #musicscience findings on the genetic architecture of musical rhythm, published today in Nature Human Behaviour, co-led with Maria Niarchou (she/her), twitterless Lea Davis, and @NoriJacoby nature.com/articles/s4156… @VUMC_Insights @VUMCgenetics A thread 1/n

Heroic effort led by @CrunchyNeuroSci to study the genetic architecture of musical rhythm!

Thanks! Congrats to @Arcane_Asunder!

Thrilled to share that our beat synchronization GWAS is featured on the September 2022 cover of Nature Human Behaviour! This massive project was co-led with Maria Niarchou (she/her), Lea Davis & @NoriJacoby and supported by @VUMC_Genetics VUMC Otolaryngology–Head and Neck Surgery NIH Common Fund nature.com/articles/s4156…

The genomics of musical beat synchronization out in Nature Human Behaviour -- beautiful artwork and a really fun collaboration! @CrunchyNeuroSci Maria Niarchou (she/her) Computational Auditory Perception Group @dan_gustavson 23andMe Research MSU TAP Lab Nori Jacoby @AngladaTort @ElseEising Capra Lab Evonne McArthur

I am excited to share our recent work published in GBE (Genome Biology and Evolution). We report that human enhancers have both ancient cores and recently evolved DNA. This combo is important for enhancer activity and functional variation across human populations. Check it out!