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New research featuring DCRI’s Steve Greene, Mark Kittipibul MD, Bradley Hammill, Adrian “WE NEED RCTS!” Hernandez, and G. Michael Felker examines clinical outcomes and financial costs of inpatient & outpatient worsening heart failure events: onlinelibrary.wiley.com/doi/epdf/10.10…

DEP Alex 🙏🏽🕊️

Further evidence for simultaneous initiation of #GDMTworks in #CKM. Incremental, fully additive, early benefits Status quo, slow, serial, sequential approach = ⬆️ exposure to excess clinical risk ⬆️ chance patient never gets prescribed the therapy at all Gregg Fonarow MD Duke Clinical Research Institute

#trasplantecardiaco #31 de nuestra Clínica de #insuficienciacardiaca de I. N. Cardiología Mx en los últimos 5 años Paciente: 19 años, Anomalía de Ebstein de la Clínica de Cardiopatías Congénitas del Adulto Gran labor de muchísima gente comprometida para cambiar la vida a los pts 🙌🏽

📌 C-LDL. Más bajo por más tiempo ES MEJOR ! No existe un límite inferior “tóxico” para el C-LDL

The benefit of finerenone is consistent across the spectrum of baseline risk in patients with heart failure and mildly reduced and preserved ejection fraction. ja.ma/3SHzjkx

🚨#heartfailure mortlity is ⬆️ Age-adjusted ☠️ increased by 146% 📈 from 1970 to 2022 🛑 We must increase our efforts to stop this trend: 1) PREVENTION, 2) Timely diagnosis, 3) Timely and OPTIMIZED treatments, 4) ⬆️ trained personnel (doctors and nurses)… ahajournals.org/doi/pdf/10.116…

💧Fluid restriction in #HeartFailure, myth or must? Current guidelines offer limited evidence & FRESH-UP study fills the gap with real-world data on fluid & sodium strategies Join our #HFA_ESC Journal Club and: ✔️Understand the rationale, study design & findings ✔️Discuss

Historical definitions of #heartfailure From Sir Thomas Lewis (Diseases of the Heart, 1933) ➡️ Universal Definition of HF (HFSA / HFA-ESC / Japanese HFS, 2021) doi.org/10.15420/cfr.2… #cardiotwitter

📌Sarcopenia (↓in skeletal muscle mass & strength) In #heartfailure ⬆︎ ☠️ 📈In 19.5% of CHF pts & >50% of Advanced HF or ADHF pts Steps: 1️⃣F ind SARC-F Q 2️⃣A ssess Handgrip test 3️⃣C onfirm MRI/CT 4️⃣S everity Walk speed Tx: exercise & maybe SGLT2i doi.org/10.1016/j.card…

Let´s BE PROACTIVE, follow these 5 core principles for a rapid & intensive OMT in our HF pts: 1️⃣Avoid delay 2️⃣In-hospital initiation is essential 3️⃣Overcome risk-treatment paradox 4️⃣Acknowledge the safety profile 5️⃣Recognize risk of omission Steve Greene Gregg Fonarow MD Javed Butler

#heartfailure improved EF ⬆️Rising prevalence 🚨Despite partial recovery, risk for MACE remains 🚦Clinical gaps and therapeutic approaches under investigation Definitions, epidemiology and more ➡️ doi.org/10.1016/j.jacc… JACC Journals Marco Metra Muthu Vaduganathan Gianluigi Savarese