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How are big proteins washed out from CSF, if they can’t go through the glymphatic system? Here is how: our new finding on glymphatic bypass || nature.com/articles/s4159… Congrats Antoine and Ben Plog and thank you to our many collaborators!

A new Science Immunology study describes a previously unknown inborn error of immunity in patients with tuberculosis due to a rare inherited deficiency in the lymphocyte surface receptor LY9 in T helper 1 memory cells. scim.ag/4mG6Zwv

A new Science Immunology study describes a previously unknown inborn error of immunity in patients with tuberculosis due to a rare inherited deficiency in the lymphocyte surface receptor LY9 in T helper 1 memory cells. scim.ag/4mG6Zwv

What if the real reason we get #sick isn’t just the germ – but something hidden inside us? Join the journey of Jean-Laurent Casanova, a doctor and #scientist who set out to solve one of medicine’s most puzzling questions: why do some people become dangerously ill from #infections

Rare #InbornErrorsOfImmunity affecting MHC class I expression can cause chronic infections & be mistaken for #autoimmune disease. New research highlights the need for infection-focused care & long-term follow-up. Review by Gadola, Ljunggren et al.: hubs.la/Q03rHl7q0

A new Science Immunology study describes a previously unknown inborn error of immunity in patients with tuberculosis due to a rare inherited deficiency in the lymphocyte surface receptor LY9 in T helper 1 memory cells. scim.ag/4mG6Zwv

Beautifully written Review on inherited HLA class I deficiency: Inborn errors of immunity affecting the MHC class I pathway for antigen presentation rupress.org/jhi/article/1/…

An infant who contracted Mycobacterium #tuberculosis revealed clinical manifestations suggestive of BCG infection. The identification of the Mycobacterium species is pivotal in determining the appropriate therapeutic regimen. From Espinosa-Padilla et al.: hubs.la/Q03s1yN_0

This review by Don Vinh highlights the diversity in intrinsic fungal susceptibility across individuals and populations, through genetic- and autoantibody-mediated processes. hubs.la/Q03kDJ-v0 📘 In our Clinical #Immunology Collection: hubs.la/Q03kFj_p0 #FOCIS2025

Therapeutic progress: Topical JAK inhibitor for refractory skin inflammation in STAT1 GOF rupress.org/jhi/article/1/…