
Daniel Castellano
@cdanicas
Medical Oncologist. Hospital Univ. 12 de Octubre. Madrid. UCM. Head GU Unit. Executive Member @GUARDconsortitum
ID: 1125754626
27-01-2013 18:02:48
7,7K Tweet
3,3K Followers
1,1K Following


1/5 How reproducible are phase III oncology trials? 📊 With Alexander Sherry Erik van Zwet Ethan Ludmir MD et al. We analyzed 632 RCTs (~496,000 pts). The data offer both reassurance and caution for clinicians and researchers. pubmed.ncbi.nlm.nih.gov/40628175/ 👇#MsaouelLab


💫🌟🎯 Stereotactic Radiation for Primary Renal Cell Carcinoma: Is It Ready for Prime Time? OncoAlert European Association of Urology (EAU) ESMO - Eur. Oncology 📌 Erdem, Hannan, veronica mollica et al. 💥 “Ablation without incision — but are we ready to let go of histology?” 🟢 SBRT delivers: • 96% local control at 5 yrs



Human kallikrein 2: A novel lineage-specific surface target in prostate cancer 🧬KLK2, a prostate-specific cell surface target, unlocked. 🔵3 therapies (bispecific T-cell, alpha-radioligand, CAR T) show strong preclinical activity. Clinical Cancer Research AACR OncoAlert Oncology Brothers



Breaking News from ph3 Embark trial👉Enzalutamide+ADT improve overall survival (OS) vs. ADT alone in Non-Metastatic HSPC #Prostatecancer Congrats to Stephen Freedland, MD neal shore & team! Earlier enza works better! Link👉 rb.gy/iyc3f2 OncoAlert UroToday.com Prostate Cancer Foundation



🧬Single-cells omics provide highly informative and refined data about cancer biology. Yet, still need a roadmap to implement into the clinical practice! Must-read insights from Michael Skinnider et al. Cell Press OncoAlert Toni Choueiri, MD David Braun Eli Van Allen Yüksel Ürün


🇪🇸 Our Spanish multicenter study on SBRT for localized prostate cancer is featured by UroToday.com ! ✅ 251 pts, 12 centers ✅ Low acute toxicity ✅ Real-world data 🔗 urotoday.com/recent-abstrac… 🙏 Thanks @UroToday for highlighting our work! #SBRT #ProstateCancer #RadOnc



Underutilization of genomic testing in metastatic castration-resistant #ProstateCancer. Pedro C Barata, MD MSc FACP Case Comp Cancer Ctr joins Neeraj Agarwal, MD, FASCO Huntsman Cancer Institute discussing data revealing that nearly half of patients aren't receiving HRR testing despite its clinical importance and expressing

PSA responses with darolutamide + ADT in the #ARANOTE trial. Dr. Fred Saad CHUM joins Neeraj Agarwal, MD, FASCO Huntsman Cancer Institute to discuss how darolutamide + ADT triples undetectable PSA rates in mHSPC vs. ADT alone (62.6% vs. 18.5%). Patients achieving PSA <0.2 ng/mL see a 90% risk

🌏 APCCC is everywhere and now it’s in Seoul! Global minds unite for prostate cancer care. Genitourinary Masterclass! Advanced Prostate Cancer Consensus Conference #ProstateCancer #Oncology #GlobalOncology OncoAlert silke gillessen aurelius omlin



Starting the day with #ASCO25 Review at Ohio State Medical Oncology with an stellar lineup of speakers with our chairs Asrar AlAhmadi, MD, MAS-CR - أسرار الأحمدي & Ashish Manne a great opportunity for an update and networking with our colleagues from Ohio! Logan Roof, MD, MS Lingbin Meng Elshad Hasanov, MD, PhD The James


Thanks for advertising Advanced Prostate Cancer Consensus Conference and do not forget that registration is now open for 2026 on apccc.org for everyone interested. And we will for the first time also accept abstracts! Stay tuned for other news!

🌟Therapeutic Targeting of MMR-Deficient Cancers🌟 🖋️ Paul Johannet, Benoit Rousseau, Carol Aghajanian, Mike Foote Memorial Sloan Kettering Cancer Center Luis Diaz Nature Reviews Cancer nature OncoAlert “MMRd tumors: an immunogenic paradox — vulnerable yet resilient” 🔵 Immune-checkpoint inhibitors


