Center for Integrated Cellular Analysis (@cegs_ica) 's Twitter Profile
Center for Integrated Cellular Analysis

@cegs_ica

NHGRI CEGS center developing methods to simultaneously measure and harmonize multi-modal single-cell data

ID: 1280622959833612293

linkhttp://www.multimodalintegration.org calendar_today07-07-2020 22:01:34

477 Tweet

1,1K Followers

17 Following

Dan Landau (@landau_lab) 's Twitter Profile Photo

🥳new pre-print alert! VEXAS syndrome deciphered - From single-cell genotype-to-phenotype mapping aaaall the way to mechanism and therapeutic vulnerability discovery! biorxiv.org/content/10.110…

Dan Landau (@landau_lab) 's Twitter Profile Photo

🍭new pre-print! In collab. with Mission Bio , we developed single-cell Genotype-to-Phenotype (scG2P) for targeted co-capture of DNA & mRNA! We explore esophagus clonal mosaicism, defining clonal structure the phenotypic impact of somatic drivers biorxiv.org/content/10.110…

🍭new pre-print!

In collab. with <a href="/MissionBio/">Mission Bio</a> , we developed single-cell Genotype-to-Phenotype (scG2P) for targeted co-capture of DNA &amp; mRNA!

We explore esophagus clonal mosaicism, defining clonal structure the phenotypic impact of somatic drivers

biorxiv.org/content/10.110…
Center for Integrated Cellular Analysis (@cegs_ica) 's Twitter Profile Photo

We're excited to welcome an incredible cohort to the 2024 Center for Integrated Cellular Analysis Undergraduate Summer Research Program in Single-cell Genomics. Check out intern bios here! multimodalintegration.org/usrp-people

We're excited to welcome an incredible cohort to the 2024 <a href="/cegs_ica/">Center for Integrated Cellular Analysis</a> Undergraduate Summer Research Program in Single-cell Genomics. Check out intern bios here! multimodalintegration.org/usrp-people
Rahul Satija (@satijalab) 's Twitter Profile Photo

Interested in 3' UTR changes in scRNA-seq? Check out our: * CPA-Perturb-seq paper * UCSC Perturb-seq tracks (see who regulates your favorite 3’ UTR!) * Seurat extension for polyA site analysis (PASTA) * Deep neural perturbation network (APARENT-Perturb) cell.com/cell/fulltext/…

Junyue (@junyue_cao) 's Twitter Profile Photo

Thrilled to introduce IRISeq, a scalable, cost-effective and imaging-free spatial genomic technique for mapping mammalian brain aging, developed by incredible Abdul AbdulAbdul and Weirong from our lab at Rockefeller University! biorxiv.org/content/10.110…

Rahul Satija (@satijalab) 's Twitter Profile Photo

Thanks to Bin Tian for such a kind and generous spotlight on our CPA-Perturb-seq work! Highlights open and fascinating questions in RNA Biology and post-transcriptional regulation - and the potential for single cell sequencing to help answer them: cell.com/molecular-cell…

Rahul Satija (@satijalab) 's Twitter Profile Photo

Our next Center for Integrated Cellular Analysis Virtual Seminar (12PM on 10/1) AbdulAbdul introduces IRISeq, a new technology to perform spatial transcriptomics in a highly scalable and cost-effective way (<$50/tissue section)- no optics or imaging required! Free registration: nygenome.zoom.us/meeting/regist…

Our next <a href="/cegs_ica/">Center for Integrated Cellular Analysis</a> Virtual Seminar (12PM on 10/1)
<a href="/Abdul_Squared/">AbdulAbdul</a> introduces IRISeq, a new technology to perform spatial transcriptomics in a highly scalable and cost-effective way (&lt;$50/tissue section)- no optics or imaging required!
Free registration: nygenome.zoom.us/meeting/regist…
Rahul Satija (@satijalab) 's Twitter Profile Photo

We are hiring for a wetlab research association position! Check it out to learn more about our lab's focus in single-cell genomics, multimodal/spatial analysis, and genome engineering. Apply/learn more at jobs.silkroad.com/NYGenome/Caree… or DM me a copy of your CV!

TDCC @genometdcc.bsky.social (@genometdcc) 's Twitter Profile Photo

Center of Excellence in Genomic Science Annual Meeting at Scripps Seaside Forum 🌅 Learn more about these CEGS Centers, their research, and outreach programs by visiting genome.gov/Funded-Program…

Center of Excellence in Genomic Science Annual Meeting at Scripps Seaside Forum 🌅

Learn more about these CEGS Centers, their research, and outreach programs by visiting 
genome.gov/Funded-Program…
Junyue (@junyue_cao) 's Twitter Profile Photo

Finally out in Science Magazine! Utilizing the cost-effective EasySci to profile 21 million single-cell transcriptomes across five life stages and diverse sexes/genotypes, we reveal aging as distinct, development-like transitions, with dramatic cell population changes in specific

Dan Landau (@landau_lab) 's Twitter Profile Photo

Excited to share a major breakthrough from the lab! D&D-seq is a new technology that bridges a key gap in single-cell multi-omics/genomics : the ability to map DNA:Protein (e.g., TFs or chromatin remodellers). Led by Ivan Raimondi, Wei-Yu Chi and Sang-Ho Yoon

Ignacio Vázquez (@ivazquezgarcia) 's Twitter Profile Photo

New year, new beginnings! I am absolutely delighted to share that I have joined @HarvardMed @MGH_RI @BroadInstitute to start my research group in Boston in January 2025! 🎉🧬🔬#NewPI #AcademicTwitter #NextChapter (1/7)

New year, new beginnings! I am absolutely delighted to share that I have joined @HarvardMed @MGH_RI @BroadInstitute to start my research group in Boston in January 2025! 🎉🧬🔬#NewPI #AcademicTwitter #NextChapter (1/7)
Rahul Satija (@satijalab) 's Twitter Profile Photo

Check out our two new papers with new single-cell tech/methods/data! 1. Phospho-seq: Multi-modal profiling of intracellualar proteins nature.com/articles/s4146… 2. Systematic Perturb-seq of signaling regulators (2.6M cells, 6 cell lines, 1500 perturbations) nature.com/articles/s4155…

Rahul Satija (@satijalab) 's Twitter Profile Photo

Interested in single cell genomics but need help getting started? Check out my lab's Single Cell Genomics Day on April 25. Talks will feature recent exciting computational and experimental advances and will be live-streamed at satijalab.org/scgd. Please RT/spread the word!

Chenxu Zhu (@chenxuzhu) 's Twitter Profile Photo

We're incredibly excited to share our new method, Paired-Damage-seq, out Nature Methods today! This technique allows us to jointly analyze oxidative DNA damage and SSBs with RNA, all at the single-cell level (1/5). nature.com/articles/s4159…

Rahul Satija (@satijalab) 's Twitter Profile Photo

Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day on Friday 4/25. All talks will be live-streamed (no registration required) at satijalab.org/scgd25

Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day on Friday 4/25. All talks will be live-streamed (no registration required) at satijalab.org/scgd25
Junyue (@junyue_cao) 's Twitter Profile Photo

Excited to share our first anti-aging intervention study, led by brilliant Zehao Zehao Zhang, Alex Alex Epstein, and Chloe Chloe Schaefer from our lab at Rockefeller University! With a cost-effective spatiotemporal analysis pipeline, we identified the aging-associated cell

Excited to share our first anti-aging intervention study, led by brilliant Zehao <a href="/Tommyz626/">Zehao Zhang</a>, Alex <a href="/alexepstein_bio/">Alex Epstein</a>, and Chloe <a href="/chloe__schaefer/">Chloe Schaefer</a>  from our lab at <a href="/RockefellerUniv/">Rockefeller University</a>! With a cost-effective spatiotemporal analysis pipeline, we identified the aging-associated cell