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Such an honor to host these amazing postdocs. thanks for another great symposium! Chelsea Lowther @accorsi_alice @marissacoconut Renee Geck @adel-aide.bsky.social Brooke N. Wolford, PhD Hakhamanesh Mostafavi @shyamsgo Tauras Vilgalys @PravruthaRaman Katie Mika and Carlos Buen Abad Najar

Finally opened a twitter to follow scientists & science.

Thrilled to share that I'll be joining the Center for Human Genetics & Genomics at the NYU Grossman School of Medicine as an Assistant Professor in December 2023! NYU Grossman School of Medicine NYU Langone Health

Incredibly grateful for the opportunity to collaborate with such a great team! We found that much of the effect of AS is in gene expression through NMD (rather than transcriptome diversification). Many unexplained eQTLs are mediated through AS and NMD! Yang's thread for details:

Tomorrow morning I will present our latest work on reference-free isoform analysis at 12334!

I am convinced that unproductive splicing (and other molecular events disrupting protein-coding isoforms) has important implications in complex and rare diseases. The challenge is to develop new approaches to systematically study these mechanisms and their effects.

Introducing ColocBoost - a new multi-phenotype xQTL and GWAS colocalization method, that can handle multiple causal variants and scale to 100 phenotypes, led by xuewei cao , and co-mentored with Gao T. Wang . medrxiv.org/content/10.110…

Excited to share our new preprint! CACTI boosts cQTL(or caQTL) discovery by leveraging correlation between nearby peaks, uncovering 51%-255% more signals than single-peak methods. Plus, a version of CACTI,CACTI-S, skips peak calling & works great when peak calling is challenging.