Something I've observed in academia but I suspect is true in industry as well: as you become more senior, you'll find that you can be much more productive if you spend all your time being a manager and letting junior people do all the real work. But after a few years of this,

So happy to finally share this work! Thank you Anna Varghese Chai Bandlamudi Eileen M O’Reilly Michael Berger Niki Schultz for all of your guidance & insight 🧬 Research Briefing: doi.org/10.1038/s41591…

1. Tertiary Lymphoid Structures (TLSs) – on demand lymphoid aggregates that assemble in inflamed tissues/cancer to regulate immunity   But how? What molecule triggers? What cells induce?   TODAY in nature nature.com/articles/s4158…   Long-term #PDAC survivor PART4 – TLSs   🧵1/25

Excited to share my analysis of the Cancer Dependency Map! My goal was to systematically identify biomarker - dependency relationships in order to identify new anti-cancer targets and understand how to stratify patients to make those targets clinically useful.

So excited to share our latest work with Sarat Chandarlapaty, Antonio Marra, Andrea Gazzo Memorial Sloan Kettering Cancer Center out today in Nature Genetics! We uncover the function and mechanism of APOBEC3-driven therapy resistance in breast cancer. 🧵 1/ nature.com/articles/s4158…