Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile
Hongzhe Sun at HKU

@chemhsun

Norman & Cecilia Yip Professor in #BioinorganicChemistry. Research on #Metallobiology, #Metallomics, #AntimicrobialResistance (AMR), Antiviral Agents (#SARS)

ID: 566399448

linkhttp://www.chemistry.hku.hk/staff/hzsun/labPage/index.html calendar_today29-04-2012 13:53:04

276 Tweet

960 Followers

643 Following

Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Please join our 3rd part of the ASI on "Metals in Biology and Medicine" next Tuesday (June 21, 2022)! Our speakers include Edward Solomon (Stanford Chemistry), Peter Caravan (Harvard University), Feng Shao (National Institute of Biological Sciences), Walter Berger (Medical University Vienna).

Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Feel honored to be invited to deliver a frontier lecture on our work from Metallomics to drug development (e.g. COVID-19) at the Institute of Chemistry, the Chinese Academy of Sciences (ICCAS). You are welcome to join on July 15 at 9 am (Beijing time)

Feel honored to be invited to deliver a frontier lecture on our work from <a href="/Metallomics/">Metallomics</a>  to drug development (e.g. COVID-19) at the Institute of Chemistry, the Chinese Academy of Sciences (ICCAS). You are welcome to join on July 15 at 9 am (Beijing time)
Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Our feature article entitled "Metal-based strategies for the fight against COVID-19", published in Chemical Communications (58, 7466). Hope 'Metals-in-Medicine' can play a role to end the pandemic. pubs.rsc.org/en/content/art…

Our feature article entitled "Metal-based strategies for the fight against COVID-19", published in <a href="/ChemCommun/">Chemical Communications</a> (58,  7466).  Hope 'Metals-in-Medicine' can play a role to end the pandemic. pubs.rsc.org/en/content/art…
Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Do you want to do your graduate study (Ph.D/ M.Phil) in the University of Hong Kong (and in the beautiful city of Hong Kong)? Please apply for it. The deadline is Dec. 1, 2022 (ONE week left).

Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Happy to see our latest work in Journal of Biological Inorganic Chemistry on the use of gold(I) drugs as a colistin adjuvant in the fight against infections by Antisuperbugs using MCR‑1 producing bacteria as an example!

Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

At last, protein targets of Cr(III) in cells were uncovered by an integrative metallo-proteomics approach (Nature Communications )! Mitochondrial ATP synthase as a direct target of Cr(III) to ameliorate hyperglycaemia stress. Please read details at nature.com/articles/s4146…

At last,  protein targets of Cr(III) in cells were uncovered by an integrative metallo-proteomics approach (<a href="/NatureComms/">Nature Communications</a> )! Mitochondrial ATP synthase as a direct target of Cr(III) to ameliorate hyperglycaemia stress. Please read details at nature.com/articles/s4146…
Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Dalton Horizon Prize (2023): "Bismuth cure for COVID-19". We are extremely delighted to be recognised by RSC DaltonTransactions. It is a reward of persistence on our original and cutting-edge research with potential to improve human health. SBIC HKU Chemistry Metallomics

Dalton Horizon Prize (2023): "Bismuth cure for COVID-19". We are extremely delighted to be recognised by RSC <a href="/DaltonTrans/">DaltonTransactions</a>. It is a reward of persistence on our original and cutting-edge research with potential to improve human health. <a href="/SBICofficial/">SBIC</a> <a href="/HKU_Chemistry/">HKU Chemistry</a> <a href="/Metallomics/">Metallomics</a>
Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Rapid emergence of @AMR pathogens highlights the urgent need to develop novel The Global Antibiotics Resistance Foundation. We proposed a dual Trojan Horse strategy, i.e. metallo-sideromycin (e.g. Bi(III)) for coping with AMR. It works beautifully. Please read the Nature Communications paper (nature.com/articles/s4146…)

ACS Publications Bio & Med Chem Content (@acsbiomed) 's Twitter Profile Photo

Nsp14/nsp10 complex is an authentic target of bismuth-based allosteric inhibitors against pan-SARS-CoV-2 infection. #ACSInfectiousDiseases go.acs.org/6T6

Nsp14/nsp10 complex is an authentic target of bismuth-based allosteric inhibitors against pan-SARS-CoV-2 infection. #ACSInfectiousDiseases  

go.acs.org/6T6
Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Happy to see our collaborative work with Xinming Yang on "Clinically used drug arsenic trioxide (As2O3) targets XIAP & overcomes apoptosis resistance in an organoid-based preclinical cancer model". The paper is featured in the cover of Chemical Science (2024, 15, 8311).

Happy to see our collaborative work with Xinming Yang on "Clinically used drug arsenic trioxide (As2O3) targets XIAP &amp; overcomes apoptosis resistance in an organoid-based preclinical cancer model". The paper is featured in the cover of <a href="/ChemicalScience/">Chemical Science</a> (2024, 15, 8311).
Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Our new arsenal against AntiMicrobial Resistance published in Nature Microbiology: Bismuth-based drugs/compd effectively sensitize Pseudomonas aeruginosa to multiple antibiotics by disrupting iron Ourhostasis. Bismuth chemistry is amusing! @OscarKuipers1 Rubén Cebrián HKU_Science

Our new arsenal against AntiMicrobial Resistance published in <a href="/NatureMicrobiol/">Nature Microbiology</a>: Bismuth-based drugs/compd effectively sensitize Pseudomonas aeruginosa to multiple antibiotics by disrupting iron Ourhostasis. Bismuth chemistry is amusing! @OscarKuipers1  <a href="/rubencebrian/">Rubén Cebrián</a> <a href="/hku_science/">HKU_Science</a>
Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Pleased to share our Perspective in J. Am. Chem. Soc. entitled "Metal-based approaches for the fight against antimicrobial resistance (AMR)": pubs.acs.org/doi/full/10.10…

Pleased to share our Perspective in <a href="/J_A_C_S/">J. Am. Chem. Soc.</a>  entitled "Metal-based approaches for the fight against antimicrobial resistance (AMR)": pubs.acs.org/doi/full/10.10…
Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

Dear junior scientists on biological inorganic chemistry SBIC we provide a platform for you to show your breakthrough work👍! You can not afford to miss the chance

Hongzhe Sun at HKU (@chemhsun) 's Twitter Profile Photo

What a fantastic Cover Art (for the fight against antimicrobial resistance (AMR) in J. Am. Chem. Soc. , #MyACSCover! Thanks Mr. Li Zhang and Dr. Chenyuan Wang for designing the cover image! Please download the paper (open access) for details at pubs.acs.org/toc/jacsat/147…

What a fantastic Cover Art (for the fight against antimicrobial resistance (AMR) in <a href="/J_A_C_S/">J. Am. Chem. Soc.</a> , #MyACSCover! Thanks Mr. Li Zhang and Dr. Chenyuan Wang for designing the cover image! Please download the paper (open access)  for details at pubs.acs.org/toc/jacsat/147…