
Siyuan Cheng, PhD
@chengsiyuan1004
Cancer biologist, Bioinformatician @LSUHS, dog dad, good husband. Developer of #CTPC #ProAtlas #HuPSA&MoPSA #PCTA
ID: 1054116864434073600
https://scholar.google.com/citations?user=1D7mdDsAAAAJ&hl=en 21-10-2018 21:06:59
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I am thrilled that our scRNAseq study on prostate cancer is published! We identified two novel cancer subtypes: KRT7 and progenitor-like and developed webApp. Check it out here: rdcu.be/dPONB npj Journals. Explore the data: pcatools.shinyapps.io/HuPSA-MoPSA/ LSU Health Shreveport @NCICancerBio



In this paper, using scRNAseq➡️ bulk RNAseq ➡️ IHC, we identified and validated two novel AR-/NE- prostate cancer subtypes: KRT7 & progenitor-like. Patients with these markers are less responsive to ADT🧐. #prostatecancer #Bioinformatics Prostate Cell News LSU Health Shreveport Research LSUHS School of Graduate Studies





Despite advances in anti-androgen therapies, resistance remains an issue. 5-15% of prostate cancer patients have UBE2J1 mutations, leading to reduced AR degradation and resistance to anti-androgen drugs. Ping Mu explains on UroToday.com: tinyurl.com/yvsvcmvx






news.yale.edu/2025/04/01/get… Thanks a lot, Jim, for the amazing article! And apologies for the small error—I’m not a urologist😆 Yale Urology

