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It is proteomics day! The UK Biobank pharma proteomics project (PPP) has borne its fruits today as three parallel publications in nature from researchers across industry and academia. Can't wait to dive into these papers. Congratulations to everyone involved 👏👏👏

Nature research paper: Plasma proteomic associations with genetics and health in the UK Biobank go.nature.com/3F2KddH

Simple blood test to predict risk of ‘every disease’ a step closer. ⁦Kaya Burgess⁩ brilliant piece on the ⁦UK Biobank⁩ proteomics release - the biggest study on proteins circulating in the blood ever thetimes.co.uk/article/79f695…

Join us TODAY! Chris Whelan presents on the Global Neurodegeneration Proteomics Consortium (GNPC). And Keenan Walker, and Carlos Cruchaga discuss high-plex protein profiling in #neuroscience research. Registration: nature.com/articles/d4422… #Alzheimers #biomarker

Reminder - all results from the UKB-PPP protein GWAS can be browsed and downloaded at: ukb-ppp.gwas.eu Full credit to Nick Lehner, Maria Ulmer (née Wörheide), Kastenmüller Lab, Matthias Arnold & Karsten Suhre for building a beautiful interface.

13 pharma companies have studied thousands of blood proteins from 54,000 people in the UK Biobank and uncovered a treasure trove of new leads on drug targets and biomarkers. My story on this massive #proteomics effort for Endpoints News: endpts.com/pharma-proteom…

Due to a server issue, the UKB-PPP pGWAS website is currently accessible to EU scientists only. Matthias Arnold & team are working to resolve the issue ASAP.

Incredibly excited to share our work using the UK Biobank Pharma Proteomics Project (UKB-PPP) data and other efforts in tonight’s #ASHG23 plenary session!! Come check it out! Olink Proteomics

I am super-excited to see this collaborative manuscript now out: Genetic determinants of blood gene expression and splicing and their contribution to molecular phenotypes and health outcomes! Pre-print: medrxiv.org/content/10.110… Data portal: intervalrna.org.uk

Congrats Stephanie Loomis for expertly leading our study of amyloid-related imaging abnormalities in the Ph3 aducanumab (Aduhelm) trials. This is the first study to systematically evaluate ARIA via GWAS & exWAS, with breakdowns by severity & APOE genotype. neurology.org/doi/10.1212/WN…

HOW DOES THE PHARMACEUTICAL INDUSTRY discover new drugs and drug targets for Alzheimer's, Parkinson's, cardiovascular disease, +schizophrenia? Dr Chris Whelan talks frankly about large biobanks, whole genome sequencing, proteomics, multi-omics, pQTLs for brain illnesses, and rare

Our latest #pQTL study using the Seer #proteomics platform just went online in Nature Communications - we share the full MS data on ebi.ac.uk/pride/archive/… Read our paper here: link.springer.com/article/10.103…

Preprint: doi.org/10.1101/2024.0…. Viral infections have been linked to an increased risk for dementia - might SARS-CoV-2 infection also confer an increased risk of dementia in segments of the population?

Proteins, proteins, proteins. How 3,000 blood proteins can help predict 10-year risk of >200 common and rare diseases, beyond genomic markers nature.com/articles/s4159… UK Biobank Nature Medicine

We’re excited to announce a pilot proteomics program with UK Biobank and biopharma collaborators to analyze 50,000 samples using our upcoming proteomics solution, Illumina Protein Prep (IPP), which detects 9000 unique human proteins. The reference dataset will be made available