#HighlightOfTheWeek Visualization of different WPD loop states in the protein tyrosine phosphatase 1B. Work by Christine Yiwen Yeh | 葉以文 Jack Greisman D. E. Shaw Research. #compchem pubs.acs.org/doi/10.1021/ac…

Co-author Christine Yeh: Pre-print: "Mapping ovarian cancer spatial organization uncovers immune evasion drivers at the genetic, cellula and tissue level" biorxiv.org/content/10.110…

🦀 rationale for novel combination therapy strategy for ovarian cancer 📊 largest patient-centered dataset to date including subcellular spatial transcriptomics 🧬 data-driven high-throughput CRISPR screens 🤖 biologically interpretable machine learning See tweetorial for more!

Happy to share my our publication is officially out! Couldn’t have accomplished all this work without our fantastic team 💕☺️

Hot off the press 6k paper! ♨️ Check out this #FridayRead in Nature Immunology. Stanford researchers profiled 2.5M+ cells in 130 tumors using 1k & 6k RNA panels, mapping high-grade ovarian cancer & revealing immune evasion mechanisms 👉nature.com/articles/s4159…

Check out this amazing work led by Noah F. Greenwald and Iris Nederlof! Very exciting multi-modal data (including spatial) on a unique trial cohort re: immune induction in breast cancer. It was an honor to contribute to this study as a fledgling rotation student back in the day.

So excited to share DR-GEM, an algorithm we created as a part of my doctoral research to address gaps we felt were previously under-appreciated in single cell genomics analysis! See Livnat Jerby's awesome tweetorial on our work!