🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Finally out! Congrats! AndHR Silvia Jimeno Pedro M. Martínez García José Terrón-Bautista J. Lieberman and G. Millán Hope we contribute to the idea of supercoiling as a key regulator of genome metabolism, and not just a side-product of DNA transactions. More to come ... cell.com/cell-reports/f…

We are appealing following a crash on Ratcliffe Ter, 8.45am Thurs 26 Jan, involving a blue Vauxhall Corsa and a cyclist. A man aged 27, the cyclist, was taken to ERI for treatment. If you saw what happened or have dash-cam please call us on 101 - Inc 0654 of 26/1/23

Could everyone in Edinburgh please RT this to maximise the chance of finding a witness of the incident? I suffered a head injury and broke a few teeth because of it and so far there has been no luck with any CCTV footage. The exact timing was more like 8:15am on that day

Hi Everyone, please see message below. Michael in our team was knocked off his bike. He has concussion and broken teeth 👇

Thanks chromatin community! We’ve been digging around in your repetitive DNA (>40,000 ChIP-seq samples) and have discovered a totally unexpected role for BRD4 and JQ1 at centromeres. Very happy to share our preprint. biorxiv.org/content/10.110…

We are looking for an enthusiastic and motivated chromatin biologist to investigate how RNA-mediated large-scale chromatin structure affects transcription. More info here edin.ac/3Loif0t

Thanks to @catherinenaug10 Nick Gilbert's Lab for hosting a pair of #SI2023 pupils for a Lab Taster Session on Tues afternoon MRC_HGU Institute of Genetics and Cancer

Come join us in Oxford as an Associate Professor in Molecular and Cellular Biochemistry. We are considering a wide range of research areas, but I would note that we have a vibrant chromatin and gene regulation community. Happy to answer questions if you are interested. Please RT!

This week we hosted John van Noort from Leiden Institute of Physics (LION) who gave a wonderful seminar on how to understand chromatin folding with single-molecule approaches. See below how they unraveled the columnar organization of our telomeres! nature.com/articles/s4158…

Would you like to do a PhD studying nuclear architecture, neuronal function and disease? Collaborative project with Nick Gilbert's Lab and Marina Chekulaeva in Edinburgh and Berlin. Closing date: 19th May, 2024. Check here for more details edin.ac/3ULweS6

Last week was another busy one in the chromatin lab with plenty of FISH, chromosome spreads to look at common fragile sites, testing of anti-SARS-CoV-2 monoclonal antibodies, and logo design for an upcoming project (more about this in the future)!

The lab is growing! We recently welcomed 3 new postdocs into the lab, Jeremy, Daniel, and Koyo🧬. Check out their bios and plans on our website chromatinlab.org/members

Tuesday is our lab meeting day! We enjoyed Daniel's exciting research updates, as well as some cakes! 🔬🍰

I keep being fascinated by these wonderful electron micrograph from Paulson and Laemmli. These apparent loops make such complex paths that are aesthetically beautiful and intellectually stimulating. Microscopy is fantastic. doi.org/10.1016/0092-8…

In 1994, Chalfie et al. expressed Green Fluorescent Protein (GFP) in living organisms. This photo shows E. coli expressing GFP (right) vs. control cells (left).Today we use this amazing tool to characterize the dynamics of proteins involved in chromatin architecture.🧬🔬 #science

We are excited to announce our new manuscript is on bioRxiv edin.ac/3z7hhBH. We use super-resolution imaging, molecular biology and polymer simulations to show that nuclear RNA forms an interconnected network of microgels. Well done everyone!

Open2C, an international team of bioinformaticians including the group of Anton Goloborodko at IMBA, recently published three new open-source software tools for data analysis in 3D chromosome biology and genomics. More about Open2C here: bit.ly/Open2C

🎉Our paper quantifying how RNA flows across subcellular compartments is published! 🎉 Read more in the preprint thread ⬇️ The paper contains an improved analysis of RNA flow rates and new collaborative work on DDX3X with @stephenfloor authors.elsevier.com/a/1jMoV3vVUPRm… Molecular Cell

Researchers from across The University of Edinburgh and Helmholtz Munich | @HelmholtzMunich learned how to communicate complex science concepts to young people as part of a week-long #EpiCrossBorders workshop Nick Gilbert's Lab MRC_HGU Edinburgh Cancer Research CMVM Research Office bit.ly/4fgt6pM

As part of the weeklong #EpiCrossBorders Symposium at IGC, CEO of T-Therapeutics Professor Allan Bradley gave a keynote talk about his experiences of translating research on both sides of the Atlantic. Nick Gilbert's Lab MRC_HGU Read more in this interview: buff.ly/3Yj5XwP