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Want to capture both transient and sustained changes of neuromodulator levels? Want to compare neuromodulator dynamics at high resolution across animals and extended periods? Happy to share our new finding on bioRxiv: tinyurl.com/bdf7ny7s (1/8)

⚡️🧠Thrilled to share our new preprint on pain-related valence cell-types + circuits — A nociceptive amygdala-striatal pathway for chronic pain aversion Check out the stellar work of Jessica Wojick, in a co-senior collab with KorbLab biorxiv.org/content/10.110… THREAD 1/13

Endogenous opioid dynamics in the dorsal striatum sculpt neural activity to control goal-directed action biorxiv.org/cgi/content/sh… #biorxiv_neursci

What an amazing experience teaching at the Neurobiology Course course with stellar students @WallsAria and Anna Brennan! Huge thanks to MBF Bioscience for loaning us the Neurophotometrics V2 fiber photometry system, which worked perfectly with our UV laser for in vivo photopharmacology.

Synapses and Circuits 2024! Thank you for a great section!! Aizenman Lab Matt Banghart Michael Higley 🧠🌈🔬 Laura Cocas watanabe lab 🔬 Juan Angueyra

1/6 Exciting news! Our paper is now online in Cell! We've developed PRESYNAPTIC sensor and silencer for peptidergic transmission. The sensor detects LDCV release events, and the silencer specifically degrades neuropeptides inside the LDCV. authors.elsevier.com/a/1jTSjL7PXqREw

Excited to share our new paper in @NatureMetabolism! OGT fine-tunes glycolysis and mitochondrial coupling in neurons via HK1, revealing new insights into energy metabolism and efficiency. 🧠🔬 #Neuroscience #Metabolism #Mitochondria : nature.com/articles/s4225…

an excellent update on current hot topics in chemical neurobiology!

Curious about the placebo effect, especially placebo pain relief? If so, check out our pre-print on placebo analgesia in mice bit.ly/3QlktPq, in which we ask how pain-modulatory neural circuits become activated in the brain to suppress pain in the absence of a drug. 1/9

It's clear that many do not understand what NIH-funded research does to improve health. It's time to revive a study published 10 years ago that provides incredible information about this. link in the comment Every single new drug approved by the FDA from 2010–2016 was built on