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How about extending the stimulus payments to non-resident aliens because, yknow, we lived here and paid taxes like everyone else??

I’m excited to share that our #CPTAC #proteogenomic adult glioblastoma study is out 🎉authors.elsevier.com/c/1cZZ05TA51Vx… What a great experience working with amazing researchers from Test Account McDonnell Genome Institute, WashU Medicine Pacific Northwest National Laboratory National Cancer Institute and many others!!

My first preprint ever is up! 😄 We show that the strength of core promoters, not it's identity (or class, or motifs) determine how it responds to its surrounding genomic environment. biorxiv.org/content/10.110…

How do human promoters sense genomic context to control gene expression? Exciting study from Barak A Cohen integrating hundreds of promoters into different loci Promoters are broadly compatible with activation in different contexts biorxiv.org/content/10.110…

Being part of preLights has been and continues to be awesome😊

Check out the latest preprint from our lab by my dear friend Siqi :) He developed a method to perform MPRAs in single cells and show that it can be used to detect cell-type specific regulation and cell-to-cell variability in cis-regulatory elements! biorxiv.org/content/10.110…

Ever wondered what could go awry when your body copies a 6 billion letter message (i.e. your #genome) 1E16 times over your lifetime? If so, checkout our #preprint on the origins and functional effects of #mutations throughout the human lifespan. bit.ly/3yT5KBz

Our paper is now out in Genome Research! Extremely grateful to Barak A Cohen and all the people who made this possible. Happy to talk to anyone who has questions or just want to discuss the paper :) genome.cshlp.org/content/early/…

We have a new version of this preprint! There are 2 key changes - we now show that scMPRA works in mouse retina (!), and we finally implemented the second U6 transcript to detect unexpressed promoters. Siqi worked really hard on this so please check it out 🙂

Our paper on insulators is out on Biorxiv! We tested the activity of insulators across thousands of genomic locations to figure out where insulators function. Oh, and I successfully defended today :) biorxiv.org/content/10.110…

This is a really nice summary of the recent papers on E-P compatibility: doi.org/10.1016/j.molc…. Also nice to see that their results support our model that interactions between CREs are strength-dependent rather than dependent on specific TFs! (from genome.cshlp.org/content/32/1/85)

Our single-cell MPRA paper is finally out! Super excited about the potential of this technology to study cell-type specific gene regulation 🥰

Super excited for the next phase of my training and to be part of this amazing group! 😊

Why do different variants in the same gene cause different forms of disease? In our latest preprint we use MPRA technology to test how two blindness-causing variants alter the function of CRX in mouse models. Work of our collaboration with Shiming Chen. biorxiv.org/content/10.110…

Excited to share my first preprint from ASHansen Lab! It's got genomics, AI, and biology - all wrapped up in a great paper. Also very grateful to my amazing collaborator, Fan, for all his hard work. Please check it out and let me know what you think! tinyurl.com/bdfvtd6f

Proud of my amazing friend for his super cool work ♥️