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The propensity of #mutationalsignatures to leave mutational hotspots serves as an estimate of the variability in their mutational probability at single-nucleotide resolution ➡️ embopress.org/doi/full/10.10… Nuria Lopez-Bigas IRB Barcelona #cancergenomics

Can mutational hotspots help to study the mutation rate variability at single-nucleotide resolution? Follow Claudia's thread on her lalest paper to know more. Congrats Claudia Arnedo Pac , Ferran Muiños , abeldavidgp and Nuria Lopez-Bigas for the great work.

🧬Hotspot propensity across mutational processes. 📰Mol Syst Biol-EMBO Press ✍️Claudia Arnedo Pac Ferran Muiños abeldavidgp Nuria Lopez-Bigas (bbglab). ➡️bit.ly/3SdCVeL 📌doi.org/10.1038/s44320… #IRBScience

Looking for a postdoc in my group @NCMMnews Nordic EMBL P'ship UiO - Det medisinske fakultet @unioslo_mn Centre for Bioinformatics, University of Oslo to enhance computational resources for regulatory genomics (JASPAR & UniBind) with deep learning. Project in collaboration with Anshul Kundaje (anshulkundaje@bluesky) & Wyeth Wasserman jobbnorge.no/en/available-j…

The genomic landscape of 2,023 colorectal cancers is out! I’m very grateful to have collaborated with such a great team on this massive project! Check all the findings here --> nature.com/articles/s4158…