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Hypoxia limits C. albicans. Anaerobiosis limits growth of C. albicans. #Antibiotic disruption of anaerobiosis drives C. albicans bloom, which can be prevented w/probiotic bacteria that respire oxygen or pharmacological restoration of anaerobiosis Andreas Baumler cell.com/cell-host-micr…

Wow, @nature has retracted the 2020 Poore et al. cancer microbiome paper that we showed (journals.asm.org/doi/10.1128/mb…) was deeply flawed. The retraction date is tomorrow so I can't yet read the official notice, but I'll update when I can Retraction Watch Professor Booty PhD

Thrilled to reunite the medical mycology and fungal immunology community in Ventura Beach in January 2025. Don't wait, go ahead and register, and submit your abstract. Link: grc.org/immunology-of-… Please RT.

I knew nothing about fungi when I started this collaboration. Special thanks to Bing Zhai and Tobias Hohl is now @fungalspore.bsky.social for the opportunity. Bing Zhai has been a great collaborator and taught me so much. This work changed my career, laying the foundation for my K99 and future lab Geisel School of Medicine at Dartmouth.

A new study from Memorial Sloan Kettering Cancer Center that explains why antifungal prophylaxis can fail and lead to life-threatening Candida infections in BMT patients. Huge congratulations to study team. #TransplantID David Andes FungalDoc: moved to bluesky @GermHunterMD @PergamIC Mihalis Lionakis Nature Medicine

Thank you Memorial Sloan Kettering Cancer Center and Emory University for highlighting our most recent work on life-threatening fungal infections in patients. mskcc.org/news/msk-resea…

For good science, one person in the collaboration should have their feet on the ground (be an expert in the field) and the other person should have their head in the clouds (full of ideas from other fields).

Bloodstream infections with Candida parapsilosis in allogeneic hematopoietic cell transplant recipients are associated with heteroresistance to the antifungal micafungin Tobias Hohl is now @fungalspore.bsky.social, DWeissLab, Bing Zhai, Chen Liao, Siddharth Jaggavarapu nature.com/articles/s4159…

Bloodstream infections with Candida parapsilosis in allogeneic hematopoietic cell transplant recipients are associated with heteroresistance to the antifungal micafungin Tobias Hohl is now @fungalspore.bsky.social, DWeissLab, Bing Zhai, Chen Liao, Siddharth Jaggavarapu nature.com/articles/s4159…

A CABBI #Conversion team at University of Illinois developed a mathematical framework to explore proteome allocation in E. coli microorganisms, providing insights into quantitative microbial physiology and the design of synthetic gene networks. 📰 ACS Synthetic Bio: pubs.acs.org/doi/10.1021/ac…

I trained a LLM for single cell RNAseq generation recently. Terabytes of data. Megawatts of GPU usage. Lights in houses dimmed all throughout silicon valley. In the end, it learned to predict cell type. As in, the predictions were only slightly better than the mean expression!

Big thank you to Trends in Microbiology, Florent Morio, Niko Papon and Anais Herivaux for highlighting our recent story on undetected heteroresistance causing failure of antifungal prophylaxis. Tobias Hohl is now @fungalspore.bsky.social Bing Zhai Chen Liao Joao Xavier nature.com/articles/s4159…

⏰ There is only one month left to apply to join us in MCB at Dartmouth! Learn more about MCB and the application process here 🧬🔬: graduate.dartmouth.edu/mcb/admissions… DartGRAD BCBDartmouth MSBDartmouth DMS_MicroImmuno

The PhD application deadline for the Quantitative Biomedical Sciences program at Dartmouth (geiselmed.dartmouth.edu/qbs/) is this coming Sunday (Dec 1). If you like bioinformatics, including translational or data structure research, QBS is a great addition to your application list.

Towards the #AI virtual cell, which would represent one the most extraordinary achievements in life science cell.com/cell/fulltext/… Cell Stephen Quake Chan Zuckerberg Initiative CZI Science Charlotte Bunne

Pls share: The BioMT Core facility at Dartmouth is hiring! Come join a great scientific community. Biochemistry Core Director: apply.interfolio.com/154316 Protein Biochemist – Research Scientist: apply.interfolio.com/161499

1) Since there is a lot of confusion about the reduction of the overhead rate on NIH grants to 15% (see here: grants.nih.gov/grants/guide/n…) I'll do a little tweetorial (or X-torial?) about it.