🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

We use Multiome and HiC to build a comprehensive single cell variant to enhancer to gene map for coronary artery disease. Join effort with Paul Chungroh Lee and IttaiEres in Nate Stitziel Lab and in collaboration with Amgen 🧪🔬🧬 Test Account medrxiv.org/content/10.110…

New method CellANOVA recovers lost biological signals and evaluates global and gene level distortions introduced from common single-cell batch correction algorithms ⁦Nature Biotechnology⁩ github.com/Janezjz/cellan… nature.com/articles/s4158…

Virtual cell models have the potential to transform biological research. Today Chan Zuckerberg Initiative released an initial set of models, including scGenePT and SubCell, designed to be easy to run and build upon. This is a really exciting time in biology. czi.co/4g1jTSa

The number of cells in single-cell transcriptomics studies grew exponentially over the years. But what about the number of donors? Let me tell you the story of my contribution to the fantastic paper of Lisa Sikkema and Karin Hrovatin. Read the paper: nature.com/articles/s4159… 1/12

Very grateful and humbled to receive promotion to tenure UVA School of Medicine! Huge thanks to my supportive mentors, colleagues, family, and talented trainees who continue to inspire me along this journey. Here’s to the work ahead!

Delineating the effective use of self-supervised learning in single-cell genomics ⁦Nature Machine Intelligence⁩ ⁦Fabian Theis⁩ nature.com/articles/s4225…

New generative model, IMPA, predicts cell morphology responses to genetic and drug perturbations, enhancing phenotypic screening and drug discovery. Corrects batch effects and models unseen perturbations. Nature Communications Mo Lotfollahi Fabian Theis doi.org/10.1038/s41467…

New expression foundation model, GET, predicts gene expression in unseen cell types and context specific TF interaction networks - pretrained on chromatin accessibility data from 213 human adult and fetal cell types. nature Eric Xing Raul Rabadan nature.com/articles/s4158…

New model for multimodal spatial omics analysis, MISO, performs feature extraction, clustering and handles large-scale omics data. Includes extensive benchmarking and application to various cancer types. ⁦Mingyao Li⁩ ⁦Nature Methods⁩ nature.com/articles/s4159…

Huge congrats to PhD student John Stubbs for successfully defending his thesis today! Thanks to the committee and everyone for their support. Nathan Sheffield UVA_BIMS 🔬🥽🎓 UVA School of Medicine

Trump's slashing of NIH indirects blocked for now in 22 states but not VA. Will the "peoples protector" Attorney General Jason Miyares stand up for Virginia researchers and doctors and their work to cure cancer, heart disease, diabetes, and more?

Thrilled to share the🥇paper from the lab ATVB: An AHA Journal. Here we continue to unravel the mysteries of the 9p21.3 CAD locus showing it drives VSMC transition into an osteochondrogenic state, promoting calcification. Clint Miller UW-Madison CRB ahajournals.org/doi/10.1161/AT…

The 9p21 risk locus — the first and most impactful CAD genetic risk factor in humans — drives VSMCs to adopt an osteochondrogenic state, promoting calcification Clint Miller Valentina Lo Sardo ahajrnls.org/3E59c3h

Latest news feature in Nature Biotechnology on recent developments in spatial biology to unravel disease mechanisms, with insights from experts in field Arutha K Nick Banovich Faisal Mahmood Parambir Dulai Jasmine Plummer, Amanda Orr etc nature.com/articles/s4158…