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I wrote a new ggplot2 extension to draw Bezier curves github.com/const-ae/ggbez…🎉 The curves are defined by a set of control points and the tangents at those points. This makes each parameter directly interpretable and the curves easy to tweak! #rstats #ggplot2

Great talk from Constantin Ahlmann-Eltze (@const-ae.bsky.social) this morning beautifully giving the intuition behind LEMUR, a computational tool for the analysis of multi-condition single-cell data! #AsconaSpatial2024 GitHub: github.com/const-ae/lemur

Very excited to announce that I started a postdoc in James L Reading's lab at UCL working on tumor immunology 🥳 So, if you are in London and want to meet for a coffee, hit me up :)

Great thread by Anshul, one of the pioneers of deep learning for biology, summarizing our preprint!

🚀Interested in doing a PostDoc in my lab? Consider applying for a🇨🇭SNSF Swiss Postdoctoral Fellowship 2024. If you have any questions, join the information event tomorrow via Zoom (register via shorturl.at/zP93m) or reach out to us via bunnelab.com! 🧬Who

The #rstats community on bluesky seems to be really picking up steam, so you can also find me over there: bsky.app/profile/hadley…

Extremely proud to see my PhD project exploring intra-tumor heterogeneity in complex karyotype AML finally out in Nature Genetics ! 🎉👩🏻‍🔬 They say that 10,000 hours make you an expert, so I guess after more than five years of work I’m half-way there 😅 ⬇️1/5 nature.com/articles/s4158…

New single-cell analysis framework, LEMUR, disentangles covariates and latent cell states from multi-condition data to predict counterfactual gene expression and identify cell neighborhoods with similar DEGs without clustering. doi.org/10.1038/s41588… Nature Genetics @wolfgangkhuber

For the Monday morning crowds :) Also, take a look at my blog post, in which I compress the full lemur package into 100 lines of code and explain the core algorithm. const-ae.name/post/2025-01-0…