Welcome to the age of generative genome design! In 1977, Sanger et al. sequenced the first genome—of phage ΦX174. Today, led by Samuel King, we report the first AI-generated genomes. Using ΦX174 as a template, we made novel, high-fitness phages with genome language models. 🧵

In a new preprint from @brianhie’s lab, the team reports the first generative design of viable bacteriophage genomes. Leveraging Evo 1 & Evo 2, they generated whole genome sequences, resulting in 16 viable phages with distinct genomic architectures.

the first functional AI-generated genomes by Samuel King Brian Hie Arc Institute has a 🔥 lineup for you over the next few weeks. stay tuned!

New from Arc Institute: the first functional AI-generated genomes. This is a conceptual breakthrough, but it may also unlock new strategies for combating antibiotic resistance.

Scientists have created the first ever viruses designed by AI, and they’re capable of hunting down and killing strains of E. coli go.nature.com/4mppvIi

We should be investing far more into AI-driven drug discovery. Every extra unit of compute has the potential to translate directly into more lives saved (and can have exponential returns). That’s the purest expression of what technology is meant to do.

The ability to design antibodies against any protein of interest has major implications for medicine, biotech, and basic science. Today, we introduce Germinal, a pipeline for epitope-targeted de novo antibody design achieving  4–22% success rates with efficient experimental

Over the past week, Arc Institute published three new discoveries that I’m very proud of. • The world's first functional AI-generated genomes. Using Evo 2 (the largest biology ML model ever trained, which Arc released in partnership with NVIDIA in February), Arc scientists

Please make me a genome but make it actually good this time.

We launched Composite eight weeks ago as the first autopilot for your browser. Since July, thousands of professionals across hundreds of companies including Tesla, Salesforce, Google, Uber, and DoorDash have trusted Composite to eliminate digital browser tasks. So they can

Today, Ekin Dogus Cubuk and I are excited to introduce Periodic Labs. Our goal is to create an AI scientist. Science works by conjecturing how the world might be, running experiments, and learning from the results. Intelligence is necessary, but not sufficient. New knowledge is

excited to share what we’ve been up to! at Periodic Labs, we’re creating AI scientists they think, design experiments, and optimize for results they also run experiments by moving robot arms in an autonomous lab it’s a fun, multi-turn task, with lots of open problems for AI

The future GDP 🇺🇸 contribution of these 50 Extraordinary aliens will be $1 Trillion+ From domestic Rare Earth Metal production, space satellite communication, hurricane disaster defense, hyper-efficient photonics energy generation, DeFi to bank billions, technology to empower

We’re building tools to support research in the life sciences, from early discovery through to commercialization. With Claude for Life Sciences, we’ve added connectors to scientific tools, Skills, and new partnerships to make Claude more useful for scientific work.

Valthos builds next-generation biodefense. Of all AI applications, biotechnology has the highest upside and most catastrophic downside. Heroes at the frontlines of biodefense are working every day to protect the world against the worst case. But the pace of biotech is against

i’ve been deeply obsessed with the question of how to make humans less fragile. several months ago i decided to leave Stanford to research and deploy the biological machine learning methods that can get us closer. can finally share that i’ve been on the founding team

Let’s gooo Yash Patil Applied Compute

We are actively recruiting for two positions at the interface between biology and generative design. Backgrounds of particular interest are in protein biochemistry/evolution and synthetic genomics/biology. Please consider joining us! 1/n

Today in nature, in work led by Aditi Merchant, we report the ability to prompt Evo to generate functional de novo genes. You shall know a gene by the company it keeps! 1/n

HUGE CONGRATS Aditi Merchant 🥳🥳