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We are thrilled to announce our new publication in Cell today. We go from a human variant JAK1 discovered by Turvey lab in 2017 to unveiling a novel #neuroimmune axis in the airway. sciencedirect.com/science/articl…

Great to see another family with STAT6 GOF disease diagnosed and treated with targeted therapy!

Pleasure to write a commentary with Louise Rowntree and Carolyn Cohen for very interesting work by Ford et al on activation based TCR profiles w repeated COVID vaccination - good news for successive CD8 T cell recruitment nature.com/articles/s4159… and nature.com/articles/s4159…

We just posted a new inborn error of immunity on medRxiv describing a patient with ASXL1 deficiency. Please let us know what you think and if you know of other patients who may have this condition. This was a great partnership with @CatherineMBiggs and Kobor Lab

Malaysia only has 7 clinical immunologists, despite an estimated 26,000 cases of primary immunodeficiencies (PIDs), a group of nearly 500 genetic disorders. Clinical immunologists request recognition as subspecialists to improve diagnosis and treatment. codeblue.galencentre.org/2024/01/15/mal…

Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond dlvr.it/T1Wwyp #immunology

HKU Paediatrics co-organised the Heep Hong Society 60th anniversary conference. The Theme of the conference was Embracing Diversity: Flourishing wellness in all kinds of mind. over 800 participants- healthcare, education, social work, government officials, parents and NGOs etc.

📢 JEM introduces its first-ever Associate Editorial Board! We welcome Elena Hsieh Elena Hsieh, Caroline Menard Caroline Menard, Stefanie Spranger Stefani Spranger, and Franklin Zhong (LKCMedicine). Learn more 👉 hubs.la/Q02hVpx20

Dengue outbreaks can affect 390 million persons yearly. In a trial involving 16,235 persons in Brazil, the live, attenuated, tetravalent Butantan vaccine was efficacious in all age groups at 2 years. Read the full trial results: nej.md/3vTJ3Qu

EXTENDED DEADLINE FOR ABSTRACT SUBMISSION We are very pleased to announce that the abstract submission deadline for the UPAM Diamond Jubilee 2024 Scientific Symposium has been extended to 18 February 2024! Please submit abstract to paed.hku.hk/diamond/en/

A research team from HKUPaed discovered that γδ-T cell-derived exosomes exhibited dual anti-tumour activities by carrying cytotoxic and immunostimulatory molecules that can directly kill tumour cells and stimulate the immune system. For more: buff.ly/3Tb60GO

A successful APSID School on ‘Inborn Errors of Immunity’ at Tokyo, Japan today, organised by Prof. Hirokazu Kanegane and team! Fantastic cases, engaging discussions, and lots of collaboration.

Fantastic Inborn Errors of Immunity School at APSID in Tokyo! Brilliant minds and precious flowers blooming! With Dr Jaime S Rosa Duque, MD, PhD 🩺 Daniel Leung Satoshi Okada APSID

Gigi Notarangelo giving the Pres Lecture at APSID. A tour de force summary of studies Gigi and his lab have done on RAG deficiency over several decades! Superb!!

Dr Luigi Notarangelo from NIAID, NIH, USA delivered the 4th. Prof. Yu-Lung Lau oration at the APSID-JSIAD Congress, Tokyo, Japan ‘One gene, many phenotypes – RAG deficiency: immune deficiency with immune dysregulation’

[WPIW]Exploring Diseases through Art - A Touring Exhibition on PID at Pharmaceutical Colleges" made its debut at China Pharmaceutical University on April 21st! This marked a significant step in PID awareness within pharmaceutical education.World Primary Immunodeficiency Week IPOPI

Early diagnosis is key in IEI. By catching diseases early, we can provide early treatment and change prognosis. In this regard, NBS has been fundamental to imltove the outcome for SCID patients. Thank you so much Antonio Condino for your big contribution in this area for LATAM

28 July is The World Hepatitis Day. The Hong Kong Liver Foundation (lnkd.in/gcPZ7J9m) launched the mobile truck for viral hepatitis screening program 🚛 to help our citizens screen for hepatitis B virus infection 🦠 in Hong Kong 🇭🇰EASLnews EASL Education AASLD World Health Organization (WHO)

Delighted to be part of the #QUEST trial consortium. Marked reduction in composite of HHF and CVS mortality among #HFrEF patients given #qiliqiangxin when compared to placebo group. Full paper on Nature Medicine: nature.com/articles/s4159…

Researchers from HKUMed have made a breakthrough in cancer treatment with the world’s first hybrid photosensitive therapy using γδ-T exosomes. For more: hkumed.hk/faf555