
Darian
@darianyang
Postdoc in Computational Biophysics: UCPH
ID: 1176847542652481541
http://darianyang.github.io 25-09-2019 13:15:06
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137 Followers
469 Following




We are absolutely thrilled to finally share our new structure from Clemons Lab @Caltech of escape mechanism of the smallest phages (φX174) by breaching the peptidoglycan layer, now out in Science! science.org/doi/10.1126/sc… 🧵 In this thread, I'll give you a sneak peek of the YES complex👇🏼







Register now for the free WESTPA Workshop Pitt Chemistry, June 20-21. Explore rare event simulations like protein folding, ligand binding, & chemical reactions with our open-source software. Perfect for those using AMBER, NAMD, GROMACS, etc. Reg info: forms.gle/6gJF6jJ72iexbD…

Another great BPS with both vintage and fresh WESTPA developers/users from the Lillian Chong Rommie Amaro Daniel Zuckerman Terra Sztain, PhD and Ahn Labs!





We often think of an "equilibrium" as something standing still, like a scale in perfect balance. But many equilibria are dynamic, like a flowing river which is never changing—yet never standing still. These dynamic equilibria are nicely described by so-called "detailed balance"

Watch your protein parameters go brrr 🚀 Check out our preprint on applying reinforcement learning (RL) to optimize Protein Language Models: arxiv.org/abs/2412.12979 With Maria Artigues, Andi, Talal Widatalla, Marc Güell and Noelia Ferruz

My Latest work from @Gronenborn_lab. Using 19F NMR, we developed a multiplexed assay for tracking small GTPase activity. This method enables real-time, simultaneous monitoring of multiple proteins under physiological conditions. Check it out in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…