We are hiring at all levels! Postdocs & PhD students (computational & wetlab) for exciting single cell and spatial genomic projects to unravel mechanisms of fibrosis and identify novel drug targets and biomarkers for translation. Join our terrific team Please RT 👇👇

Great catching up with Rafael Kramann, MD PhD Christoph Kuppe @sikandhayat David Schumacher Laura Wienecke @jonepstein1 @DevBioAcademic and others ImmunoFibHF in Heidelberg this weekend

Our new paper is out led by Felix Schreibing and Monica T. Hannani with Sikander Hayat Costa Lab - @costalab.bsky.social Julio Saez-Rodriguez and many more, it took a while after the preprint but we are all happy that it's finally out 🔥🔥#COVID19 #SARS-CoV2 #teamwork👇👇 👇frontiersin.org/articles/10.33…

Happy to share our new review: Multiomic Spatial Mapping of Myocardial Infarction and Implications for Personalized Therapy ATVB: An AHA Journal Thanks Rafael Kramann, MD PhD for the opportunity and outstanding support!

Thrilled to see our new study out in Cell Reports led by Konrad Hoeft Gideon Schaefer bit.ly/3XJ5MXB. We investigated #platelet-#macrophage-crosstalk in #fibrosis identifying a platelet-instructed SPP1 macrophage subset that controls fibroblast activation. 1/9

We are so thrilled to see our new study out in Cell Reports today (bit.ly/3XJ5MXB)! We investigated #platelet-#macrophage-crosstalk in #fibrosis identifying a platelet-instructed SPP1 macrophage subset that controls fibroblast activation. 1/11

I am very happy to share our new study out in Cell Reports today (bit.ly/3XJ5MXB)! We investigated #platelet-#macrophage-crosstalk in #fibrosis identifying a platelet-instructed SPP1 macrophage subset that controls fibroblast activation. 1/12

Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner dlvr.it/Sjk438

Our ⁦Circulation Research⁩ review by ⁦Felix Schreibing⁩ and Theresa Anslinger on fibrosis in heart and kidney 🔥🔥🔥👇👇👇 ahajournals.org/doi/10.1161/CI…

🙌🙌terrific work from Sikander Hayat and Yang Xu you should check it out ! Fast model free standardisation and integration of single cell transcriptomics👇👇

Our study on sublethal #necroptosis signaling in liver inflammation and #HCC led by Mihael Vucur has been published today in Immunity . cell.com/immunity/fullt… Please check it out, it is open access. 👉Quick wrap up: (beware of Zombie Cells🧟‍♂️)

Exciting news for #Immunology and #Cardiology enthusiasts! Join us at #ImmunoCardiology2023 this September 21-23 in beautiful Bar Harbor, Maine to explore the intersection of these fields and discover the latest breakthroughs in #hearthealth research. Register now! #ImmunofibHF🩵

Registration is OPEN: jax.org/education-and-…

Fabulous early morning hike with the Aachen team at our ⁦ImmunoFibHF⁩ Immuno Cardiology meeting ⁦The Jackson Laboratory⁩ Bar Harbor ⁦Turgay Saritas⁩ ⁦Sikander Hayat⁩ ⁦David Schumacher⁩ ⁦Acadia National Park⁩

I totally agree, what a terrific talk by Rong Fan!! Thank you so much for such an exciting discussion on our way back to Boston!

1/16) We are excited to share our recent paper “ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts” published today @Jclinicalinvest led by Konrad Hoeft and Lars Koch jci.org/articles/view/…

Nice last evening in St Louis at the St. Louis Cardinals ballpark with the lab Sikander Hayat Turgay Saritas David Schumacher and the whole ImmunoFibHF consortium⚾️⚾️

Happy to share our new paper Nature Communications led by Konrad Hoeft Tore Bleckwehl Sikander Hayat. Label-free single-cell RNA multiplexing leveraging genetic variability. nature.com/articles/s4146… 🔥🔥👇👇 Tweetorial will follow

In @Circres we describe a novel Echocardiography-Guided Method for Induction of Myocardial Ischemia/Reperfusion. Check out the full study here: doi.org/10.1161/CIRCRE… Great collaborative effort with @leuschnerlab, @lavinelab, The Jackson Laboratory Rafael Kramann, MD PhD DZHK Germany ImmunoFibHF

🚨 New Resource Alert! From @uniklinik_aachen & Novo Nordisk — we present an Integrated Single-Nucleus Atlas for Human Heart Failure 🫀 A comprehensive map built from 1.8M nuclei across 195 patients. Preprint: medrxiv.org/content/10.110… 🧵Here’s what’s inside: