David Darrow, MD (@daviddarrow) 's Twitter Profile
David Darrow, MD

@daviddarrow

#neurosurgeon at the #UofM working to #translate #neuromodulation into therapies for #neurologic and #psychiatric #diseases

ID: 17314718

linkhttp://www.hermandarrowlab.com calendar_today11-11-2008 17:41:55

445 Tweet

1,1K Followers

872 Following

U of M Neurosurgery (@umnneurosurgery) 's Twitter Profile Photo

Impact of Percutaneous Radiofrequency Rhizotomy Temperature on Trigeminal Neuralgia Relief | Coauthors include faculty members Dr. Andrew Grande and Dr. David Darrow (last author) | #trigeminalneuralgia | sciencedirect.com/science/articl…

UMN Biomedical Eng (@umnbme) 's Twitter Profile Photo

Minnesota folks: Tune into tonight's KARE 11 6:30pm broadcast for a story about how nerve stimulation is helping patients w/ paralysis move again — a finding from the clinical trial of Prof. Tay Netoff (Tay Netoff), David Darrow, MD & team.

World Neurosurgery Journal (@worldneurosurg) 's Twitter Profile Photo

June '23 News: Impact of Percutaneous Radiofrequency Rhizotomy Temperature on Trigeminal Neuralgia Relief David Darrow, MD sciencedirect.com/science/articl…

David Darrow, MD (@daviddarrow) 's Twitter Profile Photo

🚀 Big news from Herman Darrow Lab Our latest study in Neuroimage presents a game-changing method for analyzing brain signals, offering a deeper understanding of brain function. This technique is a leap forward for #human #neuroscience UMN Medical School sciencedirect.com/science/articl…

🚀 Big news from <a href="/HermanDarrowLab/">Herman Darrow Lab</a> Our latest study in Neuroimage presents a game-changing method for analyzing brain signals, offering a deeper understanding of brain function. This technique is a leap forward for #human #neuroscience <a href="/umnmedschool/">UMN Medical School</a> sciencedirect.com/science/articl…
hhrinstitute (@hhrinstitute) 's Twitter Profile Photo

The #RestorativeNeurotraumaLab, co-led by David Darrow, MD and Samuel Cramer, and the #ESTAND trial. #ESTAND participant and former #motocross racer, Evan Faucett talks about how his life is improving with the help of an epidural stimulator. The story is linked in the comments!

Xin-Yuan Yan (@xinyuanyan) 's Twitter Profile Photo

Anxious people tended to explore more, viewing their environment as rapidly changing. In contrast, apathetic individuals explored less and saw changes as random check our new paper on BPCNNI 🫰sciencedirect.com/science/articl…

Damien Fair (@drdamienfair) 's Twitter Profile Photo

Alert!!!! Anybody out there?!?! “An Action Networks Model for Pain” We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it. 👉 thread below 🧵 osf.io/preprints/ps...

Alert!!!!  Anybody out there?!?!

“An Action Networks Model for Pain”  

We propose a new model for chronic pain  — and highlight two functionally connected cortical networks that could revolutionize how we treat it.  

👉 thread below 🧵  

osf.io/preprints/ps...
Damien Fair (@drdamienfair) 's Twitter Profile Photo

Chronic pain affects 1 in 5 adults, yet current treatments — meds, DBS, SCS — often fail. Motor cortex stimulation sometimes works. 🤔 But why? We now have the answer: it’s not just the motor cortex. It’s how the brain integrates pain with action.

Damien Fair (@drdamienfair) 's Twitter Profile Photo

Two newly characterized brain networks are critical: * SCAN (Somato-Cognitive Action Network) * AMN (Action-Mode Network) These aren’t just "motor" or "cognitive" areas. They are core pain-processing hubs, tightly linked to action planning and control.

Damien Fair (@drdamienfair) 's Twitter Profile Photo

Figure 1 (attached) shows how these networks: • Interdigitate with traditional motor areas • Align closely with pain activations (r=0.73) • Vary dramatically between individuals These are non-sensory pain networks. That’s why classic targeting misses.

Figure 1 (attached) shows how these networks:  

• Interdigitate with traditional motor areas 
• Align closely with pain activations (r=0.73) 
• Vary dramatically between individuals  

These are non-sensory pain networks. 
That’s why classic targeting misses.
Damien Fair (@drdamienfair) 's Twitter Profile Photo

So, we examined it in our prior cortical stimulation patients. Two patients with central neuropathic pain. * One had electrodes over both SCAN & AMN. *One hit only SCAN. Pain relief tracked exactly with network engagement. Precision matters!!!!

So, we examined it in our prior cortical stimulation patients.   

Two patients with central neuropathic pain.  
* One had electrodes over both SCAN &amp; AMN. 
*One hit only SCAN.  

Pain relief tracked exactly with network engagement. Precision matters!!!!
Sanjeet Grewal, MD (@seizuresurgeon) 's Twitter Profile Photo

Great work by Dr David Darrow, MD and his team to try to better understand facial pain, we need more of this so that we can identify potential new treatments for our paints suffering from these disorders.

David Darrow, MD (@daviddarrow) 's Twitter Profile Photo

This is exactly the point and why the goal is to intervene at all possible levels with neuromodulation whether cortical stim #dbs #tms #ultrasound and also why understanding behavior is critical to understanding our patients in #pain Alexander B. Herman MD, PhD