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Using in-vivo and in-vitro electrophysiological recordings we deciphered that soluble high molecular weight tau is key for reduction in bursts observed in AD tau pathology. Now published in Cell! Congratulations to all of us for the great teamwork!

Where does Alzheimer’s begin in the brain? Our new study in Neuron reveals that earliest changes start deep in cortical layers 5/6, selectively affecting parvalbumin interneurons via reduced NPTX2 & GluA4. Restoring NPTX2 reversed deficits. cell.com/neuron/fulltex…

This is important to convert passive listeners into active thinkers!

Hiring! We're looking for a postdoc to join my lab at the UK Dementia Research Institute @UCL. We’re investigating neuronal and circuit dysfunction in Alzheimer's, and developing innovative new treatments. Apply here👇 shorturl.at/LpCAq #Neuroscience #Alzheimers #Postdoc #Hiring #Dementia

Facing problems head on might not always solve it but definitely gives the courage to overcome it!

The amyloid precursor family of proteins in excitatory neurons are essential for regulating cortico-hippocampal circuit dynamics in vivo dlvr.it/TLK7sb

Come join us for this super exciting event. You can't have anything better to do next Saturday 😜

Pleased to see our latest paper published. The physiological role of the APP family has been sought since its first description more than 25y ago. We show the APP family is critical for spontaneous neuronal activity in the brain by regulating synaptic NMDA receptor function.

We looking for students with an Engineering background to help design and develop an experimental arena to automate quantification of a fly behavior. See attached for more details. Please help spread the word.

"India needs scientists who can bend it like Beckham! A focused emphasis on quality and efficiency rather than quantity in research is the competitive edge that India needs to succeed." linkedin.com/feed/update/ur…

The Huntington's Disease Society of India partnering with researchers, clinicians, NGOs, governmental agencies. Bringing hope for patients and caregivers across the country and the world. Please spread the word and join this event 23-24 Aug, NIMHANS, Bengaluru HDSI

Learning without a goal! Plasticity in the visual cortex even without goal-directed training! nature.com/articles/s4158…

Looking forward to the ASET colloquium to be delivered Tata Institute of Fundamental Research on Friday June 27th by Dr. Nachiket Mor Nachiket Mor based on work done by him and Iti Bhargava which has deep relevance to mental health related policies for India

Research led by Dr Samuel Harris and Marc Aurel Busche reveals a role for the Alzheimer's-linked APP proteins in sustaining brain activity in healthy brains 🧠 The study provides insight into how their disruption could contribute to cognitive impairments👉buff.ly/KcwK7OQ

Research led by Marc Aurel Busche and Dr Samuel Harris (UCL Queen Square Institute of Neurology & UK Dementia Research Institute) has discovered that the amyloid precursor protein (APP) family is essential for healthy communication between brain cells. buff.ly/AuII6SZ

Cool work using high speed voltage imaging showing the role of CA1 interneurons in odor cue based working memory task! Congratulations Jiannis Taxidis, Peyman Golshani and all other authors!