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"NEVER forget the path of the traversing FNA needle". Liver mass in a 50/M with history of "Pancreatic Neuroendocrine Tumor (PanNET)". The flat sheets of mesothelial cells present a beautiful and eye-catching contrast with the background metastatic PanNET.

Teaching "anisonucleosis" to pathology interns - "Large Cell Carcinoma" of lung. (EBUS FNA)

Aspergillus (with its characteristic 45 degree branching) in a bronchial washing. Cytology rules ! Lola Lozano Tania Labiano @Sincita_Roy Xiaoyin "Sara" Jiang, MD (She/Her)

"Innocent Entrapment" - EBUS-FNA of a lung lesion.

Much more IMPORTANT than "Location, Location, Location" is "History, History, History". This lung FNA is of a metastasis from the patient's known Oncocytic (Hurthle Cell) Thyroid Carcinoma.

"Nuclei bent in pain" - Epithelioid histiocytes (of course a misnomer!) from a non-necrotizing granuloma on a lung FNA.

Extended HPV Genotyping and Dual Stain for triage of primary HPV screen-positive cases: Practical guidance for the cytopathology laboratory. Work done by the ACS Cervical Cancer Roundtable’s Laboratory Infrastructure Workgroup. Cancer Cytopathology Cytopathology.org ACS National Roundtable on Cervical Cancer

"Micropapillary Adenocarcinoma" of the lung involving pleural effusion. Impressive tumor cytoarchitecture with psammoma bodies. (cytospin and cell block)

A crunchy thyroid with "onion skinning", " tubular capillaries" and " chunky calcifications" - Papillary Carcinoma. (FNA)

MULTINUCLEATION in mesothelial cells is most often a reactive cytologic feature, in this case associated with lymphocytosis. (Pleural fluid, Cytospin)

NOT benign osteoblasts on FNA from a sclerotic spine lesion. Despite the innocuous appearance, these cells represent bone metastasis from the patient's known "Lobular Breast CA". (FNA)

Couldn't be more excited to announce the launch of pathlibrary.com, the virtual slide site I wish had existed during my pathology residency. You can: - Order special stains to work up cases - See annotated histologic features - Prepare for exams with board-style questions

First #PathFellowship Open House at MSK Department of Pathology & Laboratory Medicine. Please join us!

The out-of-proportion, "megalo-macro- gigantic" nucleoli of a poorly-differentiated "Hepatocellular Carcinoma". (Liver, FNA)

Glands, Acini or Rosettes? Occasionally, the vague "tigroid" smear background helps. This pancreatic FNA with IHC help was diagnosed as "Acinar Cell Carcinoma". (EUS-FNA)

Gorgeous cytomorphology of a biphasic cellular "fibroepithelial neoplasm" on a breast FNA that was confirmed to be a "Phyllodes Tumor" on excision.

A "crunchy" FNA - Papillary Thyroid Carcinoma.

A heavy "intoxication" - Pancreatic Ductal Adenocarcinoma. (EUS-FNA)

Adenocarcinoma, presenting a sharp contrast with the juxtaposed benign squamous cells in a lower esophagus brushing. Prominent solitary macronucleoli, lack of adhered PMNs and a clean slide background with absence of inflammatory debris rules out reactive condition. (ThinPrep)

"Like big balloons" - Adenoid Cystic Carcinoma. (Parotid, FNA)