🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Interested in using AI and modern in silico methods for drug discovery? My colleagues and I in Leiden have an opening for a postdoc on an exciting new project aimed at identifying novel anti-cancer therapeutics. Apply now! universiteitleiden.nl/vacatures/2024…

We are celebrating 75 Years of TEM Innovation in Eindhoven 🔬🎆 I am honoured to be part of history, both figuratively and literally (top right corner of the poster)!🤓

A rewarding collaboration revealing an entirely novel inhibitor pocket in DNA gyrase. Inhibition mechanism determined via beautiful biochemistry experiments by Leela - well done Leela! Thanks to Yehuda Halfon 🏳️‍🌈 The Astbury Centre for the final EM data collection 👍

NEWS - Old drugs new tricks – Novel approach shows “enormous potential” for rapid antibiotic discovery Innovative project to re-purpose existing drugs for their potential as antibiotics has uncovered a promising candidate okt.to/ZsjxBz Norwich Research Park Dmitry Ghilarov

🚨Super excited to share our pre-print describing how we used genomics to discover a family of anti-phage lanthipeptides from Actinobacteria 🦠 This marks a significant expansion in the number of bacterial natural products involved in chemical defense. A thread 👇: MDMLab

Bitter-sweet result. Our paper is out in Nature, but sometimes you're forced to hide your affiliation to make it happen. Viruses encode tRNAs to circumvent tRNA-targeting immune systems, like PARIS. Thanks to David Bikard, Wiedenheft Lab and the teams. nature.com/articles/s4158…

Congrats Łukasz & Yusuke, really cool to see this finally out!!

Prospective students, consider working with Michelle - she’s great and the science is super cool 😎

It was hugely rewarding to host David this Summer, and I hope his experience will further boost his interest in research. Cannot recommend IUSS more

My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses. (👇 I recommend sound ON for the video 🎹) 1/

CBASS is NOT an abortive-infection system, but nonetheless eliminates viruses in archaea. Great work from Deepak Kumar, Himani, Dana Vassover Noam Golan and Leah Reshef. Looking forward to feedback from the community. biorxiv.org/content/10.110…

Have you ever wanted to design protein binders with ease? Today we present 𝑩𝒊𝒏𝒅𝑪𝒓𝒂𝒇𝒕, a user-friendly and open-source pipeline that allows to anyone to create protein binders de novo with high experimental success rates. Bruno Correia Sergey Ovchinnikov biorxiv.org/content/10.110…

Are you: 1. Looking for a fully-funded PhD 2. Interested in virus genome replication 3. Excited about RNA-protein interactions 4. Keen to master techniques in structural biology and single molecule, fluorescence-based imaging (TIRF, FRET) Then get in touch! And please RT

Well done Roger! So pleased for you!

doi.org/10.1038/d41586… Check out our story! From inseparable undergrads in Belgrade to PhDs scattered across the globe, FFDS (Four Friends Doing Science) kept us inspiring each other, no matter the distance. Can you guess who’s who😆? Boris Stojilkovic Milica Jelicic Miloš Tišma

Two days visit to YSBL Biology at York such a great structural biology community💎❄️🔬. Very exciting to see so many people interested in topoisomerases & drugs!

Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of Jon Markert tinyurl.com/setd2

We discovered 3 RNA families that form homo-oligomeric RNA-only complexes! Studying nature continues to expand my wildest imagination. Read about it: doi.org/10.1101/2024.1… Vivian Wu, Svetlana Shabalina, Hyunbin Lee, Grace Nye, Eugene Koonin, Alex Gao, Das Lab chiulab stanford