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Earth was born 4.5 billion years ago and has roughly one billion years of habitability left (at which point the expanding sun's increasing luminosity will evaporate our oceans). We evolved more than 80% of the way through the window, just in the nick of time.

Stanford just found a natural alternative to Ozempic using some clever regex on the human proteome. Instead of manually searching through proteins, their one-liner “peptide predictor” regex narrowed down promising candidates. The calculation likely took just a few seconds.

Does % of lines of code written by AI models really matter? If it takes developers 10x more time & efforts to write the remaining 10%, it's unimpactful, no? What matters to me is how fast you can build great apps with AI & how easy you can keep improving and scaling them to be

To my 25 - 35 year olds, you've reached the age where people around you are starting to give up on themselves because they think it's too late. Don't let that energy rub off on you. It's not too late.

Simon Barnett the average biomedical data point is way less valuable than people think at the same time, the most important data point is much more valuable than people recognize

Happy Pi Day

Don’t compete. Compute.

This week, a math professor at MIT told me that incoming students are, on average, noticeably worse at math than they used to be. Harvard, of course, just added a remedial math class, Math MA5, "aimed at rectifying a lack of foundational algebra skills among students".

Save this as your wallpaper on your phone and watch how much your life gets better! Whos in?

Taking phones off the internet boosts mental health. People were randomly assigned to block mobile internet for 2 weeks. They socialized, exercised, and read more—and became happier, less depressed & anxious, and more focused. Being unglued from devices is good for well-being.

Communication is the ultimate meta-skill

What does interpretability look like for AI in bio?

Europe is ready to negotiate with the US. We have offered zero-for-zero tariffs for industrial goods. Because we're always ready for a good deal. But we’re also prepared to respond with countermeasures. And protect ourselves against indirect effects through trade diversion.

Ray nailed this very good write up on the current situation of the world.

Radical open-mindedness and radical transparency are invaluable for rapid learning and effective change. Learning is the product of a continuous real-time feedback loop in which we make decisions, see their outcomes, and improve our understanding of reality as a result. Being

What would happen if we deleted all IP law?

Let’s play the fame game…

Jack: “delete all IP law” Elon: “I agree” How could this work and where are they coming from? I don’t know exactly but here’s a guess: In business you can view your knowledge in one of three buckets: (A) common knowledge (B) trade secrets (C) IP (patents, copyrights etc) A

This is highly useful!

I was at an interior design shop yesterday, and the salesman was blown away by some ChatGPT-edited images of our interior I showed him. Yes, AI tools are getting very good very fast. So fast that people can’t keep up.