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Another reason why driving in Montréal is alway interesting…. Which corner are we meeting at??

I looked it up - it’s not a joke.

Congratulations to May Faraj's team for this excellent work!

After a VERY long journey we are happy to share our characterization of the MAPL KO mouse. See how MAPL loss leads to lean phenotypes, dysregulated bile acid metabolism, wild changes in the gut, ultimately leading to hepatocellular carcinoma. doi.org/10.15252/embr.…

Daniel J Drucker beat me to it! Our study in Diabetes, a research journal of the ADA 🧪 is online! Spoiler alert…we found an mRNA #translation mechanism in the #beta cell that regulates “on-demand” protein synthesis. Coolest finding-#Insulin is translationally regulated! Pls read & RT diabetesjournals.org/diabetes/artic…

Here's the thing about AI in biology: it absolutely has revolutionary potential, but any model is only as good as the data it's trained on. And there's a lot we don't know or are simply wrong about in bio. Want to truly build AI for bio? Invest in basic discovery science.

Should I be worried?

The Abstract Submission Deadline for #METPHYS2024 is only 7 days away! Multiple short talks will be selected from submitted abstracts and there are two travel awards from Lucid Scientific, Inc. For meeting details and registration see: sablesys.com/metphys2024-th…

Amazing visit to Kansas City!! So much great metabolism and physiology research going on! E Matthew Morris Andrew J. Lutkewitte

People often ask me which mouse model of MASLD to use or how could we can make the ones we already have more translational. You can find my opinion here: authors.elsevier.com/a/1iusW3jDgWq3…

As we gear up to release our new human islet data resource (soon I hope!), a couple of papers we’ve been fortunate to work on with colleagues in Jeff Xia’s group at McGill…both incorporating some human islet data. 1/2 academic.oup.com/nar/advance-ar…

🗓️ Mark your calendars for June 27 at 7PM! 💻️ This free webinar explores the connection between obesity and liver disease how these conditions can impact one another. Register today ➡️ liver.ca/webinars

A very nice collaborative study comparing all common mouse models of MASLD to human disease. A must read... nature.com/articles/s4225…

Don’t forget to register for this event on Friday at 9am PST / 12pm EST. We’ll be giving a demo of humanislets.com. Thanks to the(sugar)science for hosting!

Our latest paper just out @PNAS! We report the first biological function for the gene Zfp697/ZNF697, as a regulator of muscle regeneration. University of Michigan Medical School Institute for Heart and Brain Health Umich Pharmacology Karolinska Institutet #myotwitter pnas.org/doi/10.1073/pn…

🚨 Award alert! 🚨 The Canadian Islet Research and Training Network is currently accepting nominations for the CIRTN mentorship and leadership awards! All members of the Network (PIs, trainees, staffs, etc.) are encouraged to submit nominations for these awards! More details here: islets.ca/awards/

Great opportunity for postdocs going on the job market soon to network, highlight your work, and visit beautiful Montréal!

Fantastic resource for the diabetes and islet research community from a great team led by XX

Reminder that our obsession with journal names as a lazy proxy for "impact" is new. Here are the key papers that led to the GLP-1 Lasker Award for Svetlana Mojsov: Mojsov et al JBC 261:11880 1986 Mojsov et al JCI 79:616 1987 Mojsov et al JBC 265:8001 1990 Journal of Biological

Leaving X. For so many reasons. Find me on BlueSky instead. Dr. Jennifer Estall