Dr Dermot McGovern
@doc_ibd
Professor & Director Precision Health.๐ฎ๐ช๐ฌ๐ง๐ฟ๐ฒ๐ช๐บ ๐งฌbiomarker & Rx discovery. Biotech. โฌ๏ธ DIE in research. LFC, volleyball, Irish Rugby. Views my own. YNWA
ID: 4062770898
30-10-2015 00:04:20
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IBD Genetics Digestive Disease Week #DDW2025 session. First up from our lab - Dalin Li presenting on UC vs CD and other phenotypes. More than 100 loci distinguish these phenotypes. PRS are different across phenotypes. Some novel mechanisms implicated. IBD at Cedars-Sinai.
Next up IBD genetics session Digestive Disease Week #DDW2025 Ashley Beecham presenting novel findings through local ancestry approaches in our Hispanic studies. NOD2, HLA implicated & novel finding implicating RIPK2 pathway in complicated CD on African ancestry. IBD at Cedars-Sinai Maria T. Abreu
๐ our Poster of Distinction on #IUS in ASUC (Sa1816)! #DDW2025 IBD at Cedars-Sinai InternationalBowelUS iUSCAN Digestive Disease Week
3rd presentation from IBD at Cedars-Sinai in the Digestive Disease Week #DDW2025 IBD genetics section Minsuk Kim presenting on a multiplex African American family with IBD and SpA implicating a frameshift variant in IFNAR1 in driving disease in this family.
Prof Yoichi Kakuta - Tohoku University & former lab member IBD at Cedars-Sinai group presenting on NUDT15 variants effects on pregnancy in IBD. Provocative findings suggesting utility of pre-conception testing for NUDT15. Great to see him doing this important work.
Busy 1st day #DDW2025 for our group: 3 ๐งฌ oral presentations followed by computational pathology & radiomic posters suggesting clinical utility in ASUC, post-op CD recurrence, EIMs & others. Lots more to come with AI/ML in histopathology and radiomics. IBD at Cedars-Sinai Phillip Gu
Day 2 DDW. Another busy day. V. nice of #DDW2025 organizers 2 put our lab IBD at Cedars-Sinai AI posters back 2 back 2 back. Radiomic features assoc with UC2CD dx switch, multi-modal model for predicting PSC, & visceral/subcutaneous fat assoc. with disease extent and behaviour in IBD
Afimkibart (TL1-A inhibitor) demonstrated efficacy for objective EP in moderate-severe UC #colitis in phase 2b clinical trial w no dose response, presented by Dr Vipul Jairath MBChB DPhil. The competition in this MOA class is intensifying #DDW2025 #IBD
Anti-TL1-a 3.0! Duvakitug demonstrated efficacy primarily for endoscopic endpoints in mod-severe #crohnsdisease in a first of its kind in #IBD basket trial (parallel UC, CD). Well tolerated Vipul Jairath MBChB DPhil #DDW2025 #IBD
๐ฉ Take home from our talks Christopher Gardner Digestive Disease Week is the importance of โฌ๏ธ fibre intake & โฌ๏ธ variety of dietary fibres consumed as they all have differing benefits for host & microbiome. Dietitian support is ๐ for those struggling with symptoms/concerns on high fibre diets ๐ฅฆ
Great day at Anfield meeting Mo Salah Mohamed Salah and lifting the Premier League trophy with family. Well nearly! Liverpool FC 20 times Champions of England. #YNWA โCampione, Campioneโ
๐๐๐๐ ๐๐ฎ๐ฅ๐ญ๐ฎ๐ซ๐ ๐๐๐ฒ ๐๐๐๐ A vibrant celebration of Zambiaโs cultural heritage at the University of Zambia! From traditional music and dance to food and art, the event showcased unity, identity & sustainable development through culture. #UNZACultureDay2025 #UNZA
Congratulations Jonathan Segal #TOTMUN ! Enjoy! Better season than Arsenal! I think Angie has played a blinder conning everyone all season and then releasing the Mourinho version of Spurs in the final!! Man U ha ha ha! Happy days!
