❤️ Weight & HbA1c Reductions associated with mortality & cardiovascular benefits Meta-regression of 44 trials ⚖️ Each 1 kg weight loss = 3.4% ↓ mortality risk 🩸 Each 1% HbA1c ⬇️ = 7.6% ↓ mortality risk 📉 Effects regardless of drug class dom-pubs.onlinelibrary.wiley.com/doi/full/10.11…

The efficacy of intermittent scanning continuous glucose monitoring in the elderly*: A case-control study. *Older people Older people with diabetes benefit from is-CGM. HbA1c drops sustained for 2 years, few stop using it. More support for CGM in older age! #DiabetesCare

The SURMOUNT-MMO trial is underway to test if #tirzepatide can reduce heart attacks, strokes, heart failure, and death in adults with obesity. This global study will enroll ~15,000 people at risk for cardiovascular events and is the first trial to see if an incretin medication

Presented at #ENDO2025: In 15 patients with primary aldosteronism, baxdrostat (a second-generation, nonimidazole aldosterone synthase inhibitor) resolved or reduced the severity of hypertension, excessive aldosterone production, and hypokalemia. Full SPARK study results:

New Primary Aldosteronism Guidelines - simpler, streamlined, and hopefully more pragmatic. academic.oup.com/jcem/advance-a…

I Am Taking a GLP-1 Weight-Loss Medication-What Should I Know? Useful article for patient education jamanetwork.com/journals/jamai…

CGM initiation has increased over time but remains <10% among insulin-treated older adults with T2D. Substantial racial, ethnic, and socioeconomic disparities were observed. via Diabetes Care, a research journal of the ADA 🌟 American Diabetes Association doi.org/10.2337/dca25-…

❗️Tirzepatide meets primary and secondary outcomes in its CVOT (SURPASS-CVOT)❗️ 🔹A first for CVOTs - comparing to dulaglutide (established benefit) 🔸Statistical analysis allows for comparison to putative placebo 🔹1ry outcome HR 0.92 p=0.086 🔸2ndry outcome HR 0.84 0=0.002

📉 What happens after stopping anti-obesity meds? Meta-analysis Significant weight regain begins 8 weeks after discontinuation Continuing through 20 weeks. 🔁 Regain most notable with GLP-1 RAs ⚠️ Need for long-term strategies beyond medication alone bmcmedicine.biomedcentral.com/articles/10.11…

📢 Obesity associated with risk of atrial fibrillation 🔍 10-year cohort of 392,000+ adults Obesity increased AF risk by 43%. ⚠️ Only ~27% of this was mediated by conditions like diabetes & hypertension 73% was a direct effect. 🧠 #Preventobesity dom-pubs.onlinelibrary.wiley.com/doi/full/10.11…

Now Dr. Navar debates that ApoB should be measured over LDL 🫀 Apo B & LDL can be discordant but ApoB identified risk greater than LDL 🫀 ApoB is a Better assay, don’t need to fast & LDL is not that accurate 🫀Guidelines say check in MetSyn because discordant 🫀ESC says ApoB ⭐️

Early Treatment of Insulin Resistance Using Tirzepatide New study in sixteen participants who took Trizepatide showed: 1️⃣ HbA1c decreased from 63.4 to 43.6 mmol/mol (7.95% to 6.14%) 2️⃣ Body weight decreased by 4.9 kg. 3️⃣ Muscle mass, fat mass and fat percentage significantly

💊 Pill Power: 50 mg Oral Semaglutide Delivers Big Weight Loss — OASIS‑2 Trial - - - 📍 JAMA Internal Medicine, Aug 4 2025 — 68‑week, double‑blind RCT in Japan & South Korea. Dose: Once‑daily oral semaglutide 50 mg vs placebo + lifestyle support. Population: Adults with

Proud to share our latest milestone! Our paper on DIANA – Diabetes Novel Subgroup Assessment Tool is now published in PLOS Digital Health! 🔗 Read here: journals.plos.org/digitalhealth/… What is DIANA? A web-based precision medicine tool we developed to: ✅ Identify endotypes in Type

Overprescribing in older adults with diabetes is common & risky. The eDMED study will test whether CGM-guided medication de-intensification in care homes can improve safety and quality of life in people aged ≥65. Julia Mader🇺🇦🇺🇦🇦🇹🏳️‍🌈🇪🇺🇮🇱🇺🇦🇺🇦 Prof Kamlesh Khunti link.springer.com/article/10.100…

Our paper led by Gaurav Gulsin 💡 Retinal screening could help detect subclinical cardiovascular disease earlier in T2D. 👁️ Early signs of diabetic retinopathy were linked to silent heart disease 🫀 Higher coronary calcium ❤️‍🩹 Early LV dysfunction nature.com/articles/s4159…

Mangoes are back on the menu of people with type 2 diabetes Prof Kamlesh Khunti Sarah Ali FRSA 👩🏻‍⚕️👩🏻‍🎨 Muhammad Ali Karamat Dr. Shashank Joshi SAHF.ORG.UK SAMIT GHOSAL Punith Kempegowda @DiabeUK UHB Diabetes

GLP-1 receptor agonists in kidney transplant recipients with pre-existing diabetes: a retrospective cohort study GLP-1 receptor agonists were associated with better graft and patient survival. Clinical trials are needed to confirm these findings thelancet.com/journals/landi…

Preexisting Diabetes and Pregnancy: An Endocrine Society and European Society of Endocrinology Joint Clinical Practice Guideline | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic ⁦Dr. Rahul Baxi⁩ ⁦⁦Dr Sandeep Rai⁩ academic.oup.com/jcem/article/1…

Androfem Testosterone approved by MHRA - what’s the tea 🫖 & can you now get it on the NHS? MHRA approves testosterone cream for UK postmenopausal women lawleypharm.com.au/news/mhra-appr… Ref:Testosterone replacement in menopause thebms.org.uk/wp-content/upl… Global Consensus Position