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Excited to share that I have been promoted to Associate Professor with Tenure! Wouldn’t have been possible without my wonderful trainees, mentors, colleagues, and the unfaltering support from Vijay Rathinam! Thank you all!!! Special thanks to those who wrote the support letters!

Exciting opportunity to join @Umasschan @Umass__Medicine Division of Cardiovascular Research - please RT

The latter part of my thesis work on RNA binding proteins and T cells is out in Science Magazine ! Here we find that one of the most conserved elements in the genome helps determine how your immune system responds to pathogens. #ScienceResearch science.org/doi/10.1126/sc…

UMass Chan Medical School seeks the next generation of scientific leaders! Join our research community as a UMass Chan Early Independence Fellow. Get 3-5 years of support. Apply by Dec 1: academicjobsonline.org/ajo/jobs/28425 UMass Chan Medical School RNA Therapeutics Institute

📝Delighted to share our latest review article on emerging inflammasomes. Great collaborative work by our postdocs Abhimanu Pandey+Jerry Li, and our students Manjul Gautam+Aritra Ghosh!😊 onlinelibrary.wiley.com/doi/full/10.11… #immunity #infection #cancer #autoinflammation

Everything you wanted to know about the Big Three DNA Sensors: AIM2, cGAS, TLR9. Several suppritive characters also discussed. A must read authoritative review by Fitzgerald. Kate Fitzgerald nature.com/articles/s4159…

Fantastic news - congratulations to Victor Ambros UMass Chan Medical School and Gary Ruvkun Matt

Our department is hiring! nature.com/naturecareers/…

Happy to share the final chapter of my PhD UConn Health out today in Nature Immunology ! Here we uncovered a noncanonical function of the glucose transporter GLUT4 in regulating RLR signaling in muscle and adipocytes #metabolism #Immunology Nature Portfolio nature.com/articles/s4159… 1/

So excited to have this paper out now! Pyroptotic EVs “transplant” gasdermin pores from dying cells onto bystander cells, propagating pyroptosis and inflammation. cell.com/cell/abstract/… @uconnresearch UConn Health 1/3

Congrats to Skylar Wright, who led the work with Puja Kumari Puja Kumari and Victor Fraile Agreda & everyone. Thanks to our fantastic collaborators Jianbin Ruan Jianbin Ruan, Katia Cosentina Cosentino Lab - Molecular Cell Biophysics, Beiyan Zhou Beiyan Zhou, and Priya Vanaja @kailasanvanaja 2/3

Full-text link: authors.elsevier.com/a/1kMQgL7PXqSmX 3/3

New paper from Vijay Rathinam's lab! Congratulations to all the authors! It was great to be a collaborator on this exciting study!

Gasdermin pores on extracellular vesicles spread cell death bit.ly/3BXHUuJ

We are happy to share that our work on cystic fibrosis and integrin clustering has been published PNASNews CFTR dictates monocyte adhesion by facilitating integrin clustering but not activation | PNAS pnas.org/doi/10.1073/pn…

Thrilled to start 2025 with our latest findings! Felicia Chan Yersinia invades macrophage cytosol to activate caspase-11 when caspase-8 or YopJ are inactive cell.com/cell-reports/f…

In the latest issue! Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells dlvr.it/THlY1m

Extracellular vesicles transport gasdermin pores, amplifying inflammatory cell death dlvr.it/TJCYdf #immunology

I'm happy to announce that our paper describing the first in human tissue application of inCITE-seq, to assess nuclear levels of RNA-binding proteins, and key regulators of the blood brain barrier (b-Catenin and NF-kB) is now available online nature.com/articles/s4159…

Congratulations to the 12 UConn and UConn Health faculty who were recently inducted into the Connecticut Academy of Science and Engineering. today.uconn.edu/2025/03/case-c…