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This data is so grim not even making a plot could make me feel better about it, but I tried...

Delighted to see this published by Donagh Egan as part of his 4th year BHLS thesis UCD Medicine supported by bruce.moran. Donagh identified retinoic acid signalling as a novel target in p53 mutated EC and is now a PhD student Precision Oncology Ireland 👏👏authors.elsevier.com/c/1foooKfi8svjc

"The steps in this budget are welcome but our students and faculty will continue to seek parity with their counterparts in other EU countries. In particular the €500 increase for PhDs is grossly inadequate."

Finishing up my PhD in 2012 I had a stipend of €18k. A decade later my students have a stipend that is only marginally higher (€18.5k, 3% increase). In the same time period rent for a single room in Dublin has gone up almost 70%. This is completely unsustainable.

Excited to share our latest review on the #multiomics approaches to decipher the #tumourmicroenvironment at the #singlecell level. Systems Biology Ire Precision Oncology Ireland AstraZenecaUK Donagh Egan @KreilederM Vadim Zhernovkov @KateGlennon4 Simon Dovedi Donal Brennan

New SBI article out from Donagh Egan et al! This paper demonstrates how regulon-based characterization of cell states provides robust and functionally informative markers that can deconvolve bulk RNA-seq data to identify ICI responders.⬇️ Precision Oncology Ireland #immunotherapy

🔥Hot off the presses 🔥 New review in IJMS MDPI from Soraya Epp, Shin Mei Chuah and Melinda Halasz. Well done all! #childhoodcancer #cancerresearch #neuroblastoma mdpi.com/2586578 #mdpiijms

Happy Day of Immunology 2024 from the yEFIS family 🤗

New publication! We explored BTLA and PD-1, key immune checkpoints that lead to T-cell exhaustion. Our findings show that PD-1 and BTLA signaling dampen TCR/CD3-mediated transcriptomic changes. 🔗Link: cell.com/iscience/fullt… Systems Biology Ire Genomics Data Science - SFI CRT University College Dublin MedUni Wien

Cell-specific models reveal conformation-specific RAF inhibitor combinations that synergistically inhibit ERK signaling in pancreatic cancer cells dlvr.it/TCvn1c

Dublin City Marathon childrenshealth.enthuse.com/pf/run/post/10… #dublincitymarathon #IrishLifeDublinMarathon

Tis the Season for Vivas! Our last PhDs of 2024 are Soraya Epp & Donagh Egan who both successfully defended their theses today! Well done Dr Epp & Dr Egan! Precision Oncology Ireland UCD Medicine University College Dublin #PhD #Viva #CancerResearch

Delighted to share our paper led by an amazing post doc Donagh Egan and Dr Kate Glennon who developed a framework to temporally order HGSOC tumour samples based on their proteomic expression profiles providing novel insights into metastatic progression. nature.com/articles/s4169…

Paris pollution after they added bike lanes and restricted cars