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Just out: mSMART Updated guidelines for newly diagnosed myeloma. mSMART.org Main Change: We recommend quadruplets as initial therapy for all newly diagnosed patients who are not frail. Update based on IMROZ, CEPHEUS, and BENEFIT RCT data. Mayo Myeloma

The end of an era! Ratan Tata—eternally and unequivocally a “Ratan” (precious stone), inspired millions of us. Of course, he remained at the summit as a business mogul. However, what parsed him out from the rest was his curiosity for invention, generosity, humility, &

On Sept 14, we celebrated #myeloma patients and caregivers at the #MMRF Walk/Run in MN. We raised over $170k! THANK YOU to everyone who supported this event to help accelerate a CURE for #MM! #Grateful 🫶🏾 #TogetherForACure Vincent Rajkumar Multiple Myeloma RF Hearn Jay Cho MD, PhD Anne Quinn Young

NEW in Kevin Pho, M.D.: Sukhman Shergill writes we can prevent school shootings, if only we have the courage to act. Vote for candidates who support gun safety and safe communities this November - candidates like Kamala Harris. kevinmd.com/2024/10/we-can…

What drives CPC proliferation? Led by : ash.confex.com/ash/2024/webpr… Microarrays from 136 NDMM patients identify CDCA2, DHFR and CENPF to be up ⬆️ differentially expressed. Subsequently validated in the CoMMpass data.

Hello Everyone! Please stop by Poster on 3 Gene Based Proliferation Score for prognostication of Newly Diagnosed Multiple Myeloma #ASH24 Shaji Kumar Mayo Myeloma

#ASH24 with amazing Cleveland clinic PGY2, colleagues and mentors! Akriti Jain Abhay Singh Utkarsh Goel mushtaqali @johnhanna Jame Abraham, MD, FACP Cleveland Clinic IM CCF Hematology Oncology Fellows

Your #ASHNewsDaily team IRL #ASH24 ASH

HPRSS (Hematology Patient-Reported Symptom Screen) is a simple 3-item tool measuring fatigue, pain & QoL in multiple myeloma. Fatigue & low QoL independently predict poor survival, helping stratify patients effectively. PROs matter! #mmsm shoutout to Nadine Abdallah for the

Surreal to have met my inspiration for choosing hematology, Noopur Raje. Honored to discuss and receive feedback on our work on Circulating Plasma Cells. Grateful for the opportunity to share at #ASH24! #mmsm

AQUILA trial for high risk smoldering myeloma published in NEJM today. Thanos Dimopoulos Personally for me, it is a huge milestone along 25 years of work that started in 1998. #ASH24 #ASH24VR This story below may help those interested in a clinical trialist career. 1/

Symptoms DO matter Important publications by my friend and colleague Nadine Abdallah

Excellent work in Leukemia Journal by Arwa Bohra (she/her) Shaji Kumar Vincent Rajkumar Mayo Myeloma: For myeloma #MMsm, 5% CPCs = PCL. But manual smears not always done or reliable. On PB flow, 1.16% CPCs ≈ 5% by PB smear. % CPCs exist on continuum (any are bad), but nice to have cutoff!

#Myeloma Paper of the Day: Interleukin-6 is a prognostic biomarker for #POEMS syndrome associated w/ EFS & OS (pts w/ elevated IL-6 had 17-fold increased risk of death vs. those with normal values), along with hypoalbuminemia & a high Wang score: pubmed.ncbi.nlm.nih.gov/40646134/. #mmsm