Unable to secure sufficient funding Professor Rossi was targeted for degradation.

Beautiful study - well done all!

Optimization of Phosphotyrosine Peptides that Target the SH2 Domain of SOCS1 and Block Substrate Ubiquitination pubs.acs.org/doi/10.1021/ac…

Please RT - We're after three researchers to join our expanding team to discover new targeted protein degraders to fight cancer, in the WEHI (Walter and Eliza Hall Institute) - Boehringer Ingelheim collaboration: 2x chemists (bit.ly/TPD-MedChem), 1x cell biologist (bit.ly/TPD-CellBiol). Closing 21 Feb.

One more week to get your abstracts in for the Crystal-Lite meeting

What a beautiful structure!

I am pleased to introduce DEGRONOPEDIA - a web server for degron screening. It provides complex degron information (i.a. nearby residues that may be ubiquitinated, PTMs, disorder) and allows for Machine Learning predictions of N-/C-termini stability. 1/11 biorxiv.org/content/10.110…

The first Australian #TPD meeting will be held in July! In person WEHI (Walter and Eliza Hall Institute) and online. Registration open now #DegradersDownUnder

Will be great to bring together the Australian TPD community for #DegradersDownUnder, a hybrid conference on 12-13 July 2022, in person WEHI (Walter and Eliza Hall Institute) and online. Free registration: eventbrite.com.au/e/degraders-do…

I'm really pleased to share a tool I developed with colleagues at Edinburgh University - designed to support academics in managing their research careers. 1/11

Looking for an enthusiastic medicinal chemist to join Sleebs Lab WEHI (Walter and Eliza Hall Institute) on an exciting oncology program in collaboration with an industry partner. For further details, seek.com.au/job/58192361?t…

Taking a BiTE out of KRAS G12C drug resistant tumors with cell surface drug presentation. 🙏 Craik Lab at UCSF for collaborating on our first adventure in biologics. Ziyang Zhang Peter Rohweder UCSF Helen Diller Family Comprehensive Cancer Ctr HHMI cell.com/cancer-cell/fu…

So many exciting postdoc opportunities!

💊to the Chemists looking for a Postdoc: 📢we have an open position in the targeted protein degradation & antibiotic research lab @theCrick! 🔗crick.ac.uk/careers-study/…

Excited to be part of a new collaboration to address current gaps in Australia’s #DrugDiscovery pipeline, which has been awarded $9.75m from the #MRFF. 🧵1/4

The Australian Centre for Targeted Therapeutics (ACTT) at WEHI (Walter and Eliza Hall Institute) is hiring a Senior Research Scientist (Lead Scientist, Protein Biochemistry) to help develop novel targeted protein degrader drugs. Info and applications here: wehi.wd3.myworkdayjobs.com/WEHI/job/Parkv…

Proud to sign this open letter from the Australian health sector and join with VACCHO and Victorian health leaders in support of a Yes vote in the upcoming referendum 🧵 #VoteYes

Thrilled about our latest Pseudokinase research published today in Communications Biology, showing EphB6 power in promoting cell cell adhesion through formation of intercellular tubes. Many congratulations to our star PhD student Lung-Yu Liang.

So nice to see this paper out in its final form. Hope our learnings can help you identify and confirm true, on-target degraders! Big thanks to the project team across both organisations Centre for Targeted Protein Degradation Boehringer Ingelheim Alessio Ciulli pubs.acs.org/doi/10.1021/ac…

Beautiful work by the team! Very exiting to see this out.