Annabel Short
@drbelshort
ID: 768336020618158080
24-08-2016 06:35:57
47 Tweet
99 Followers
167 Following
Happy to share this paper is finally out (after >5 years of hard work and a great team effort)! 🎉We discovered the transcriptional repressor NRSF/REST programs long-term hippocampal memory deficits/neuronal stunting after early-life adversity Cell Reports cell.com/cell-reports/f…
Just out! What factors execute enduring changes of hippocampal neurons. promoting memory deficits after early-life #stress? REST and all the rest (actually GR). REST/NRSF= a TF poised for neuronal plasticity. 👇Ali Mortazavi Johannes Bohacek @Cate_cholamine
Our SfN Journals #JNeurosci paper is officially published! jneurosci.org/content/41/4/6… Here we investigate the role of #EstrousCycle #estrogen on the effects of acute #stress on #memory . See my prior thread for details! Tallie Z Baram Annabel Short Dr. Jessica L. Bolton
Excited to finally share my scientific "baby", the result of my K99 work with Tallie Z Baram, Tremblay Lab, Annabel Short and many others, now under review and posted for your enjoyment on bioRxiv Neuroscience doi: doi.org/10.1101/2021.0…. Read on for the summary blurbs...#microglia #CRF
SO proud Dr. Jessica L. Bolton! >4 yrs of passion & smarts. 4-D live imaging of microglia-neuron interaction in neonatal mice in situ! Chronic chemogenetic microglia activation in neonates sans injection stress! yes. microglia mediate ELS effect on circuit maturation
Dear Twittexperts: how do you define a neuron (in hypothalamus) as glutamatergic? do you have a non vGlut2mRNA method you can share? TX! (see unhelpful example of vGlut2 IHC).@superkash Steve Maren 🐀🧠💭😨 Stephen Mahler Allen Institute Marina Picciotto @Herman_lab Dr. Debra Bangasser Trends in Neurosciences
Cool Annabel Short & Ali Mortazavi single-cell transcriptomics work on #stress-regulating CRH cells in developing hypothalamus. Combined data-and neuroscience-driven clustering identifies novel populations, which are specifically targeted by early-life stress. biorxiv.org/content/10.110…
Interested in early-life #stress? in humans? The QUIC, a user-friendly instrument for studying parental & environmental unpredictability-a novel important actionable early adversity- is on line. In English and Spanish! Dutch, German & Finnish versions soon contecenter.uci.edu/questionnaire-…
Thrilled to share the power of common measures in humans and experimental animals to test mechanistic hypotheses on the impact of #early life #stress on #reward sensitivity. Now out in Neuropsychopharmacology ACNP great collab with Diego A. Pizzagalli, PhD Annabel Short nature.com/articles/s4138…
Excited to share! combined data & biology-driven approaches to single cell transcriptomics of #stress-sensitive #CRH neurons identifies novel cell populations & shows selective impact of earlylife adversity. Kudos Annabel Short Ali Mortazavi Biological Psychiatry sciencedirect.com/science/articl….
Come join us for a Postdoc in California! employ #singlecell transcriptomics #merFISH and functional approaches to early-life #stress effects on #reward #amygdala #PVT. sciencedirect.com/science/articl… frontiersin.org/articles/10.33… Current folks are getting own labs! FENS Lisa Monteggia
Early-Life Adversity Blunts Reward Responsiveness in Adulthood rdcu.be/cFvEj @diegopizzagalli Neuropsychopharmacology
Postdoc work with Tallie Z Baram Ali Mortazavi Dr. Jessica L. Bolton Matt Birnie is in press!🎉 doi.org/10.1016/j.bpsg… Check out our work using single cell transcriptomics of stress-sensitive CRH neurons to identify populations impacted by early-life adversity in open access Biological Psychiatry
YAYYY, my big paper from my postdoc on #microglial pruning of stress-sensitive CRH+ neurons during early-life stress is finally out!!! This has been >5 years in the works, so big shout out to all co-authors, and especially my mentor Tallie Z Baram (thread below) cell.com/cell-reports/f…
Thrilled to share Science Magazine piece, a 10 yr obsession: developing brains get signals from the environment that shape emotional circuit maturation & impact mental health. What signals? which ones are 'bad'? how do they influence circuit refinement? science.org/doi/10.1126/sc…
Inspired by thoughtful discussions, happy to share our paper with Kevin Bath Meghan Gallo and collaborators Annabel Short Tallie Z Baram exploring the impact of resource scarcity and maternal separation in mice on maternal signals and pup amygdala gene expression doi.org/10.1016/j.ynst…
In case you missed it, check out our Tallie Z Baram lab's latest work in Nature Communications . We identified a #stress-sensitive projection from BLA-NAc, and found inhibiting it AFTER early life adversity rescued reward behavior! Find the National Institute of Mental Health (NIMH) funded study here: nature.com/articles/s4146…
Ever wondered why chronic steroid use can cause #dementia? Excited to share our paper with stafford lightman Becky Conway-Campbell University of Bristol out today in PNASNews ! Check it out below⬇️ pnas.org/doi/10.1073/pn…