PAPER OUT!! 🥳🎉💃🏻🕺🏻💃🏻🕺🏻 A redefined InDel taxonomy provides insights into mutational signatures ⁦Nature Genetics⁩ Brainchild of the amazing ⁦Gene C. Koh⁩ Tweetorial below!! 👇 1/n nature.com/articles/s4158…

Gift link --> A Wellness Company With False Claims, Global Aims and a Toronto Island nytimes.com/2025/04/16/wor…

New research from our lab on mitochondrial DNA stability RRM2B is essential for making dNTPs in non-dividing cells and its loss causes mt DNA depletion syndromes. Surprisingly, we found that RRM2B deficiency leads to a drop in dATP and dGTP. pnas.org/doi/10.1073/pn…

CRISPR-BEasy, our web tool for designing tiling libraries for base editing screens, was published last Friday in NAR (sorry, I am late). Goal: To make base editing screens accesible to all! Quick thread below with key features crispr-beasy.cerc-genomic-medicine.ca/# academic.oup.com/nar/advance-ar…

We’re #hiring, please share! A fully funded #postdoc position is available in my lab to work on DNA damage response mechanisms. Please get in touch with your CV if you are interested, closing date: 27th June 2025. More details here: candidate.hr-manager.net/ApplicationIni…

🧬New from crystal structures from our lab in EMBO J! We reveal how the FANCM enzyme, an emerging therapeutic target it cancer, has evolved to specifically recognise branched DNA and activate the Fanconi anaemia pathway of DNA repair. doi.org/10.1038/s44318… 🧵👇

“You should root for the Oilers because they’re Canadian,” says man who has confused this with the fucking Olympics thebeaverton.com/2024/06/you-sh… #StanleyCup #LetsGoOilers

Wondering what is a nucleoporin doing at repair sites? Check it out in our most recent paper in Molecular Cell! dlvr.it/TLBMbH

As northern Canada burns, southern Canada makes climate change worse by rushing through Bill 5 in Ontario and its big brother in Ottawa Bill C-5 - both will allow no regulations, special economic zones. Both bills crafted without First Nations input. 1 theglobeandmail.com/opinion/articl…

We observed that tRNA genes mutate like no tomorrow 👇

nature.com/articles/s4158…

Job alert! We have a postdoc position available in the Stelkens Lab at Stockholm University. Join us and apply experimental evolution and comparative genomics in the model system yeast to test for parallel climate adaptation. #Evolution #yeast #genomics

We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. imperial.ac.uk/jobs/search-jo…

Please RT🔁 I will be hosting this Synthetic Biology Workshop at 大阪大学PRIMe in Osaka on July 15. Great lineup of speakers: Matt Rich, Takeharu Nagai, Carl de Boer, Nika Irani, Kenji Kamimoto, @tToshimichiY. The event will be followed by a networking session🥸

When #AlphaFold2 came out, we wondered: Could it help us understand how enzymes evolve? So we tried it—and it worked! nature.com/articles/s4158…

🌎👩‍🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵 Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open. doi.org/10.1101/2024.0…

This year’s chemistry laureate Omar Yaghi was born in Amman, Jordan, in 1965 to parents who were refugees from Palestine. When we spoke to him he shared his story: “I grew up in a very humble home, we were a dozen of us in one room, sharing it with the cattle that we used to

I’m excited to share a new postdoctoral opportunity in my lab to use chromosome engineering to study the consequences of chromosomal rearrangements in iPS cells. Check out the posting below and shoot me an email if you’re interested -

✨ Latest exciting story of Schacherer Lab in nature. Here, we go beyond SNPs and built a species-wide atlas of genetic variants in yeast. With >1,000 near T2T genomes, we show how SVs shape the phenotypic landscape. Institut universitaire de France (IUF) European Research Council (ERC) CNRS Biologie nature.com/articles/s4158…

You used to be able to do this in Toronto; I've taken photos to prove it. But now you can't. So they're voting on it in commitee tomorrow. Sign the petition: change.org/FinchStoreTO