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#RheumJnlClub

How much overlap was there between enthesitis response and clinical response? Does one always predict the other? #RheumJnlClub

Rheumatology & Rheumatology Advances in Practice James Galloway It would have probably been more significant using a more comprehensive measure

Interesting question. Its hinges on your interpretation of the figure 4 in the paper. My sense is that enthesitis response does correlate with the overall response but it is by no means an absolute parallel…

Agree

Rheumatology & Rheumatology Advances in Practice These pooled data looks really promising. But so far we are not sure of the relevance in the current treatment landscape. Really looking forward to H2H trials. Most interesting vs. IL-17A-inhibition ☝️

Rheumatology & Rheumatology Advances in Practice academic.oup.com/rheumatology/a… #RheumJnlClub

Head to head studies that separate out MDA components- definitely. Very good point Dr. Fabian Proft

Rheumatology & Rheumatology Advances in Practice Hey everyone, this is Fabian a rheumatologist from Berlin Germany with a special interest in axSpA and PsA especially new treatment options, RCT‘s, cohort studies and modern imaging modalities. #RheumJnlClub

Rheumatology & Rheumatology Advances in Practice Thank you for joining us today! #RheumJnlClub #InternationalNursesDay a double celebration!

Curiously not even SPARCC captures spinal entheseal points. Interesting thought.

News: EULAR Guidelines on Intraarticular Therapy EULAR has published evidence-based recommendations on the use of intra-articular therapies (IAT) based on the literature review and recommendations of a multidisciplinary international task force. bit.ly/3covoo7

NEW: D’Agostino et al. use Power Doppler #ultrasound to investigate the response of synovitis to IL-17A inhibition with secukinumab in patients with active PsA. Watch Prof D’Agostino provide an overview of the study in our first video abstract 🤩 👉 bit.ly/3rzBD0J

Fuel for day 2 of #mrcp revision via Redber Coffee

And the Association for the Study of Medical Education meeting in glorious Aberdeen (bias alert 🏴󠁧󠁢󠁳󠁣󠁴󠁿) abstract deadline is 31/1 asme.org.uk/events/asm2022 Kathy Cullen James Galloway Charlotte Davies

Two new papers published in Rheumatology & Rheumatology Advances in Practice today look @ the impact of #COVID19 & #lockdown measures on #rheumatology patients in the UK & Europe: Inflammatory #arthritis: doi.org/10.1093/rap/rk… RMDs: doi.org/10.1093/rap/rk… Available #openaccess

AURORA 2 results were presented at #ACR21 - a continuation study of voclosporin in 116 active Lupus Nephritis pts randomized to either PBO or voclosporin. After 36 mos the VOC group had stable GFR and reduction in proteinuria bwnews.pr/3EHQjP1

🏥 Today, we're proud to unveil the new rooftop of the Denmark Wing building at King's College Hospital! #TeamKings #TuesdayMotivation

Is PMR the Next Indication for Tocilizumab? About half of patients with steroid-dependent PMR were able to get off steroids altogether when they were started on tocilizumab (Actemra) infusions, a randomized phase III trial showed. bit.ly/3BZuVoe

Tofacitinib in 15 pts w/ early diffuse skin Scleroderma. Tofa downregulated STAT3 (macrophages, DCs) & IFN (fibroblasts) & MYOC/CCL19 (adventitial fibroblasts); well tolerated & trend to improved mRSS scores (ns) bit.ly/3ykynZu