Thank you, Dr. Nandi for your incredible mentorship!! So lucky to have examples like you to look up to!

Starting residency in Pediatrics and Medical Genetics CHOP Pediatrics Residency Program today!! So grateful to everyone who helped me get to this point: Hansol Kang, family & friends, everyone in Eric Joyce, mentors and the Penn MSTP. Excited for what's ahead!

2024 WORLD CHAMPIONS 🏆

Excited to share our work in collaboration with the Eric Joyce and @RanganLab highlighting the role of Stonewall in chromatin organization in Drosophila female germline, now published and featured on the cover Genes & Development. bit.ly/3VG7jic bit.ly/3L1Pghx

Heat wave has me wishing for cooler times. #blueridgeparkway

I’m thrilled to share that our work from the VA Research is finally out in Science Magazine ! We dive deep into the genetic architecture of 2,068 traits using data from the VA Million Veteran Program, comprising 635,969 Veteran. science.org/doi/10.1126/sc…

We are organizing a free virtual workshop on Python tools for the analysis of single-cell neuronal data. Please RT and register if interested! #Single_Cell #Neuroscience #Bioinformatics

Happy to share work with Maxime TORTORA on modeling the physical chemistry of cohesin loop extrusion! biorxiv.org/content/10.110…

Excited that our paper is now out at Genome Research (genome.cshlp.org/content/34/8/1…)! We’ve since expanded upon our analyses of cell type-specific mRNA decay & looked at miRNA targets 😎 Thanks to our reviewers & editors for improving our work & to my coauthors Erik and John Murray !

First preprint from the lab 🚨 How can enhancers regulate target promoters across vast genomic distances, and what is the role of cohesin loop extrusion in the process? biorxiv.org/content/10.110… (1)

Beyond thrilled to present our O-MAP—now *published* Nature Methods (!!!) O-MAP is a powerful new method for biochemically "dissecting" the subcellular microenvironment around an RNA of interest, using off-the-shelf parts and standard manipulations. 🧵 nature.com/articles/s4159…

Excited about these incoming ⭐️s to our GI fellowship program! The future is certainly bright. @PennGIHep ACG Gastroenterology AASLD

My colleagues and I just published a paper in eClinicalMedicine evaluating effects of vaccination on long COVID risks in children and adolescents during the Delta and early Omicron periods. These data were from the RECOVER network including 21 pediatric hospital networks from

ft. Jailynn Harke, Jeewon Lee, Son C. Nguyen, Staci Rakowiecki, Rebecca Yunker, Doug Epstein, Eric Joyce (Penn Genetics), Arian Arab, @Melike_Lak (Penn Epigenetics) & Siewert Hugelier (UPenn Physiology) Molecular Cell cell.com/molecular-cell…

The first cancer-related story from our group Weill Cornell Medicine is now published in Molecular Cell. We investigate the role of hyperconnected 3D regulatory hubs in controlling oncogenic programs and properties in glioblastoma and also across 16 cancer types. cell.com/molecular-cell…

Presented on trends highlighting the need for tools to triage APCT usage in acute Crohn’s management. Grateful as always to mentors like James Lewis #DDW2025 #IBD

CHOP & Penn Medicine have delivered the first-ever personalized gene editing therapy for a patient with CPS1 deficiency, marking a major milestone in the application of CRISPR-based treatments. Learn more about KJ & the future of personalized medicine: ms.spr.ly/6015SZLAx.

In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by U.S. FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,

🚨New preprint from the lab🚨 🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK. biorxiv.org/content/10.110…