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🚀 Exciting results from a phase II trial show sintilimab + bevacizumab, and CAPOX as a promising first-line therapy for RAS-mutant, MSS metastatic CRC!🔬 eClinicalMedicine – The Lancet Discovery Science Colorectal Cancer Alliance Fight Colorectal Cancer #Onco404 #Oncology #MedTwitter #ColorectalCancer #ClinicalTrials

📢 Out in eClinicalMedicine – The Lancet Discovery Science: Our latest paper shows that education quality plays a stronger role than years of education in brain health and dementia, highlighting the importance of country-level disparities over individual factors. Proud of this work! 🧠📚🌍authors.elsevier.com/sd/article/S25…

Global landscape and trends in lifetime risks of haematologic malignancies in 185 countries: estimates from GLOBOCAN 2022 Lifetime risks of haematologic malignancies show considerable variations across regions, necessitating country-specific strategies thelancet.com/journals/eclin…

Global trends in men's and women's acceptance of intimate partner violence, 1999–2022: an analysis of population-based survey data from 83 countries There was heterogeneity in changes in IPV-related attitudes across countries over the last 20 years thelancet.com/journals/eclin…

Interaction between influenza vaccine and statins affecting risk of rhabdomyolysis in Taiwan: a nationwide case-centred analysis Recent #flu vaccination was associated with increased risk of statin-associated rhabdomyolysis within 7 days post-vaccination thelancet.com/journals/eclin…

Breaking through the mind-body divide: patient priorities for interoception research This broad scoping study establishes new, transdiagnostic, patient-led priorities for the developing field of #interoception in #psychiatry thelancet.com/journals/eclin…

Treatment decision algorithms for #TB screening and diagnosis in children hospitalised with severe acute malnutrition: a cost-effectiveness analysis These TDA approaches are highly cost-effective for the vulnerable group of children hospitalised with SAM thelancet.com/journals/eclin…

The relationship between obesity and obstructive sleep apnea in four community-based cohorts: an IPD meta-analysis Most adults with #OSA do not have obesity, with 44.4% having overweight and 23.5% having normal weight or underweight thelancet.com/journals/eclin… #sleepapnoea

Let’s build care CCF(India) …let’s all join hands Developing IBD counsellors in low- and middle-income countries: bridging gaps in patient care - eClinicalMedicine thelancet.com/journals/eclin… The Lancet eClinicalMedicine – The Lancet Discovery Science ScienceDirect Arshdeep Singh

Understanding the causes of postpartum haemorrhage is crucial to provide appropriate treatment and services. In a new study, authors identify and quantify the various causes and risk factors for postpartum haemorrhage: hubs.ly/Q03jSTNg0

The impact of the PEPFAR funding freeze on HIV deaths and infections: a mathematical modelling study of seven countries in sub-Saharan Africa The sudden cessation of #PEPFAR funding likely results in tens of thousands of #HIV deaths and new infections thelancet.com/journals/eclin…

Mitoxantrone in combination with clofarabine (MITCL) in children, adolescents and young adults with relapsed/refractory acute leukaemia: a phase I/II trial MTD was 35 mg/m2/dose x 5 days and was safe, well-tolerated and resulted in an 85% CR rate thelancet.com/journals/eclin…

Community-engaged interventions significantly improved HBV clinical outcomes! Exciting work led by Prof Dan Wu Institute for Global Health & Infectious Diseases SESH Global @unc Coalition for Global Hepatitis Elimination NOhep World Hepatitis Alliance eClinicalMedicine – The Lancet Discovery Science The Lancet Gastroenterology & Hepatology sciencedirect.com/science/articl…

Community engagement and chronic viral hepatitis public health interventions: a systematic review and meta-analysis Community engagement—actively involving stakeholders in tackling health challenges—shows promise in enhancing #hepatitis outcomes thelancet.com/journals/eclin…

Incidence and safety of abortion in two humanitarian settings in Uganda and Kenya: a respondent-driven sampling study Refugees in these contexts have little access to WHO-recommended methods of abortion, and the need for safe abortion services is high thelancet.com/journals/eclin…