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Optogenetics – for which Karl Deisseroth and Ed Boyden won the @Breakthroughprize – is revealing how networks of neurons drive our actions, with implications for both medicine and robotics. scitechdaily.com/how-simple-com…

BREAKTHROUGH REPORT: Super-resolution expansion microscopy in plant roots (Michelle Gallei, Sven Truckenbrodt, Caroline Kreuzinger, et. al.) doi.org/10.1093/plcell… ASPB #PlantSci

.Yongxin(Leon) Zhao will use Magnify Expansion Microscopy to map optic nerve fibers as part of a collaboration to make whole eye transplants a reality. cmu.edu/mcs/news-event…

“Expansion microscopy gives you opportunities that aren’t available with anything else.” Elie Dolgin reports on a decade of #ExM, feat Ed Boyden. go.nature.com/40QawzC

Legit question: It's great that people are working on AI alignment but are there also people thinking about how to make sure we end up in the Star Trek post-scarcity society and not the Blade Runner corporate dystopia society?

Fantastic deep dive on our mission to map entire human and mouse brains, and the #connectomics field by Xander Balwit. New brain imaging tech, including what we're building E11 Bio, is critical for tackling intractable brain disorders -- and maybe even solving intelligence.

With a pair of new methods, Ed Boyden is expanding the capabilities of expansion microscopy so researchers everywhere can see more when they look at cells and tissues under a light microscope. MIT Science MIT Brain and Cognitive Sciences Nature Communications mcgovern.mit.edu/2025/02/18/see…

Whole-ExM for super-resolution imaging of entire embryonic and neonatal mouse bodies under conventional confocal microscopes pubs.acs.org/doi/full/10.10…

MIT’s Ed Boyden is pioneering methods like expansion microscopy to create detailed 3D maps of neural structures, enhancing our understanding of the brain's networks to maybe even fathom life's meaning. 🧠

Ten years of bigger samples, better views mcgovern.mit.edu/2025/03/03/ten… Thank you so much Jennifer Michalowski McGovern Institute for including our lab's contribution in your remarkable piece about what I believe is the most revolutionary method for studying tiny, fascinating apicomplexans.

Fun with worms on WIRED wired.com/story/openworm… We've been thinking about how #celegans can revolutionize science again, together with Kording Lab 🦖 Ed Boyden and many other (also find our preprint on arXiv.org )

🎥Revisit the discussion on the intricate complexity of brain circuitry with Ed Boyden, renowned MIT professor and director of the Synthetic Neurobiology Group, as he seeks to understand human existence. youtube.com/watch?v=WrL4eV…

5- Ed Boyden Ed Boyden argued that true understanding will require biologically accurate computer simulations of the brain—models that combine anatomy, physiology, and molecular dynamics. Such simulations could offer insight into cognition, emotion, and even consciousness.

The awesome power of expansion microscopy 😆

The peer-reviewed version of expansion in situ genome sequencing is now out in Science! The news is bittersweet – when we first revealed this last September, I never guessed it would be my final paper in academia, but a lot has changed. A few parting thoughts:

A new combination technique enables DNA sequencing and high-resolution imaging in intact cells — offering new insights into progeria and aging. broad.io/expansion-in-s… Jason Buenrostro Fei Chen Lab Ajay Labade Caroline Comenho zack chiang Science Magazine

Thrilled to announce that our work on Expansion In Situ Genome Sequencing (ExIGS) is now published in Science Magazine! ExIGS allows us to sequence DNA and image proteins with super-resolution directly within single cells. science.org/doi/10.1126/sc…

ExIGS advances the field of "expansion genomics," dramatically reshaping how we see and understand genome organization by bridging scales, uncovering hidden details, and asking entirely new biological questions.#ExpansionGenomics #SpatialGenomics

Super excited that Expansion In Situ Genome Sequencing (ExIGS) is out now in Science Magazine ! Check out the paper to see what can be revealed by sequencing the genome in its native position and high-res imaging its interactions with nearby proteins. science.org/doi/10.1126/sc…

Researchers combined in situ sequencing with expansion microscopy to get more spatial insight into how stretches of the genome interact with proteins in the jam-packed nucleus. cen.acs.org/analytical-che…