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Have a look at our new paper on the role of CozE proteins in S. aureus Maria Disen Barbuti Grangeasse Team @CamiloPerezC6H6 Jan-Willem Veening xue liu Daniel Straume @a_ducret

PBP4 is required for serum-induced cell wall thickening and antibiotic tolerance in Staphylococcus aureus dlvr.it/T8WX8P

1st preprint from the Microbiology UCC APC Microbiome Ireland team, pulled together by Lizzie Ledger 🥳🥳 A neat story showing role of Pbp4 in Staph cell wall thickening under the stress of serum exposure, with ‘belt, braces and elasticated waist’ evidence. Wellcome @scienceirel

Interactions with #fungi can suppress or promote bacterial fitness. Yu-Ying Phoebe Hsieh Harmit S. Malik &co uncover a widespread form of antagonism, in which fungi sequester Mg2+ to lower fitness of gram -ve #bacteria, impacting #colistin resistance #AMR #PLOSBiology plos.io/4czsqd3

Course dinner #AMGDJuly24

Just finished an amazing week at #AMGDJuly2024. If you have an interest in bacterial genomics but not sure how to get started, this is the course for you. Fantastic course, well designed and executed by David W. Cleary

Do you want to run a microbial GWAS but are put off by installing a dozen different bioinformatic tools, are unsure about best practices, and how to transform the list of threshold passing variants into a neat annotated table? Then we have just the thing for you!

Latest chapter in the MspA story is out mBio Lead by Dora Bonini we show #staph MspA interacts with SpsB, which cleaves and modifies LtaS. This is crucial for LTA homeostasis and S. aureus pathogenicity Ruth Massey School of Cellular and Molecular Medicine🏳️‍🌈😷 MRC Centre for Medical Mycology journals.asm.org/doi/10.1128/mb…

Very happy to see this out in mBio. Our little MspA in S.aureus affects LTA synthesis regulating LtaS processing via SpsB, with implications on cell cycle progression

In this work, @bugsinblood and Lizzie Ledger show that host-triggered cell wall remodeling in S. aureus promotes evasion of phagocytosis by neutrophils. #mBio journals.asm.org/doi/10.1128/mb…

Just a couple of days left to apply for these postdoc positions!!

New paper alert! Capsule is dependent on LPS structure for its surface localisation, and this interplay is critical for serum resistance. Microbiology Society #publishingforthecommunity Naoise McGarry microbiologyresearch.org/content/journa…

📢 Attention antibiotic tolerance researchers! Our GIANT review of 50+ years' of clinical antibiotic tolerance data is now available online in Clinical Microbiology Reviews. Check it out here: journals.asm.org/eprint/UUSIDYA… ASM Dr Jo Hobbs Ashley Deventer Claire Stevens

Excellent analysis of why new antibiotics don’t make it to patients. Plazomicin (Achaogen) financial post-mortem ⁦John H. Rex, MD⁩ amr.solutions/2024/10/14/pla…

We are very excited to announce our latest work on how MRSA conquers antibiotics. We show that high-level resistance to methicillin requires S. aureus to utilise an alternative mode of cell division to ensure its survival! Sheffield AFM Group Abimbola_Olulana doi.org/10.1126/scienc…

Latest from the lab, driven by Lizzie Ledger. Crossover in antibiotic resistance activity between oxacilin and daptomycin. …. All roads may lead to Rome in some places but for S. aureus they all lead to Agr activity!! biorxiv.org/content/10.110…

This is concerning:🚨Emergence and Spread of Clostridioides difficile Isolates With Reduced Fidaxomicin Susceptibility in an Acute Care Hospital academic.oup.com/cid/advance-ar…

New review on S. aureus and fatty acids, written in collaboration with Maisem Laabei, Nathan Palk, and Emily Rudolph. Big thanks to Microbiology Society for publishing. microbiologyresearch.org/content/journa…

Energized into session 2: How do antibiotics kill bacteria? Edward Douglas Imperial Department of Infectious Disease is casting light onto the mode of action of polymyxin. #LINEsymposium2025

📢 paper - a new class of RIPK1 inhibitors. Lots of with here, with structure of it bound to RIPK1, biochemistry and more! Was fun being part of this with Tate group and many others. pubs.acs.org/doi/10.1021/ac…