🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

👉 MAP 2025 Scientific Co-Chairs Mariam Jamal-Hanjani, Lisa Derosa, and Joaquin Mateo highlight why your abstract matters — ⏰submit by 10 June and be part of the Molecular Analysis for Precision Oncology Congress 2025 in Paris. #MAP2025 🔗 ow.ly/uvh250VNq6L

Now online! Immunotherapy-related cognitive impairment after CAR T cell therapy in mice dlvr.it/TKk22q

🧠 Excited to share my main PhD project! We mapped the regulatory rules governing Glioblastoma plasticity using single-cell multi-omics and deep learning. This work is part of a two-paper series with Omer Ali Bayraktar , Oliver Stegle and Moritz Mall groups. Preprint at end🧵👇

How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵

Absolutely thrilled to share with you the final version of EPIclone, out now (open access) in nature. This has been an amazing collaboration with the lab of Lars Velten (@larsplus) at Centre for Genomic Regulation (CRG) nature.com/articles/s4158…

Predicting expression-altering promoter mutations with deep learning | Science Magazine science.org/doi/10.1126/sc…

Presented at #ASCO25: A 3-year structured exercise program after adjuvant chemotherapy for colon cancer improved disease-free and overall survival, physical functioning, and fitness, as compared with health education alone. Full CHALLENGE phase 3 trial results:

The loss of Y-chromosome in men affects the immune system's T cells and helps explain higher risk cancer mortality nature.com/articles/d4158…

I am deeply saddened by the passing of Prof. Gazi Yaşargil (1925–2025), the father of microneurosurgery. What an inspirational career devoted to the betterment of medicine and humankind, a legacy that will be carried onward. Rest in peace, Gazi Hocam.

Nature Portfolio Arturo Bujarrabal Dueso George Garinis CECAD Cologne Uniklinik Köln Bujarrabal-Dueso, A., Garinis, G.A., Robbins, P.D. et al. Targeting DNA damage in ageing: towards supercharging DNA repair. Nat Rev Drug Discov (2025). doi.org/10.1038/s41573…

1/14 On behalf of the amazing team in Jonathan Weissman's Lab, we’re excited to share PEtracer (biorxiv.org/content/10.110…) a prime editing-based evolving lineage recorder compatible with both scRNA-seq and high-resolution imaging readouts in intact tissue. By applying PEtracer in a syngeneic mouse

📣 Join us in Paris, 15-16 September, for MAP2025! The Scientific Co-Chairs invite you to the Molecular Analysis for Precision Oncology Congress 2025—a must-attend event for researchers & clinicians. ⏰ Register by 16 July for early rates. #MAP2025 🔗 ow.ly/M6Z050W9TfK

🚨Chemo treatment upgrade!🚨 Check out our approach to modernise chemotherapy treatment published today in Nature Genetics. From CNIO Stop Cancer Tailor Bio Cancer Research UK nature.com/articles/s4158… More details 👇

🚀 What do genomic Transformers actually learn about biology? •What knowledge do they hold at random init, after pre‑training, and following fine‑tuning? •We dove deep into every attention head to find out. 📄 Preprint live now “Interpreting Attention Mechanisms in Genomic

Don’t miss the next YO4YO Virtual Session with Ranjit Bindra,MD/PhD & Emre Kocakavuk, MD, PhD 📌 How to move from bedside to bench to biotech 📅 8 July 2025 🕒 15:00–16:00 CEST 🔗 ow.ly/eF7I50Wi97y

Our team in Cologne is looking for a postdoctoral fellow to work with us on the next generation of machine learning algorithms for cancer evolution and chromosomal instability! For details, see here: iccb-cologne.org/groups/schwarz… BIFOLD Uniklinik Köln

Final version of nature paper on mutational signatures for colorectal cancer. nature.com/articles/s4158… Important implications for early onset colorectal cancer. Check out paper or video below. Thanks as always to Cancer Grand Challenges + team Wellcome Sanger Institute and Ludmil, Marcos UC San Diego

Very much looking forward to #ESMO25 in the 😎 city of #Berlin! Huge increase in abstract submissions, and the team is currently working hard on putting together the best scientific program for you! Make sure to join us: with my co-chair Toni Choueiri, MD FabriceAndre The Netherlands Cancer Institute OncoAlert

So excited to share this with you all!😃Rama Khokha and I revisit a core assumption in cancer biology: is tumour heterogeneity a reflection of disorganization? Our thoughts on how self-organization shapes tumour tissues, and why that matters for oncology: nature.com/articles/s4156…