Pleased to see our collaboration with Dra. B. Malnic (USP) published! Congrats to Elisa in our lab! "Depletion of Ric-8B Leads to Reduced mTORC2 Activity" pubmed.ncbi.nlm.nih.gov/32392211/

only a few more days before the deadline of our PhD position in computational biology at NCMM! you'll join a wonderful research team and an exciting project to develop new methods for network analysis: jobbnorge.no/en/available-j… #PhDposition @NCMMnews

Remember March, the endless month? That was the month that the #covid19 #pandemic became real, at least where I work @UMassMedical Broad Institute. Suddenly we were working from home, and a bit lost. So ... this new paper happened. Here's the story. 1/n pnas.org/content/early/…

Multiway Enhancer-Promoter Interactions by Pranitha Vangala, check it out for some great #generegulation insight cell.com/molecular-cell…

together with Camila Lopes-Ramos from Harvard Biostatistics I'll be editing a Special Issue on gene regulatory networks in the journal Cancers. submissions are welcome in 2021: mdpi.com/journal/cancer… via MDPI

Congratulations Raya Shu | RNA nerd for this excellent work: FMRP links optimal codons to mRNA stability in neurons pnas.org/content/early/…

A fantastic write up of AlphaFold2

Look up Cambridge and Boston folks! Sky cleared up just in time to see Saturn and Jupiter from the Broad Institute

Estudante ou pesquisador em bioinfo no Brasil? Olha só o #BrazWebinars com uma seleção excelente de palestrantes! Amanhã tem! bioinfo.icb.ufmg.br/BrazWebinars/h…

Você já conhece a Revista Brasileira de Bioinformática? Não?! Tem muita coisa legal por lá, incluindo eu e a Elisa falando sobre vias biológicas. Vem conhecer! bioinfo.com.br/vias-biologica…

We're in a transition moment in this pandemic We're coming off highs of the worst surge of infections we've ever had Cases are high but starting to fall in much of the nation This moment raises lots of questions With one big one: What happens next? Thread

Excited to share our paper published in Nature Neuroscience. With #scRNAseq, machine learning, and #Slideseq, we were able to reconstruct the mouse olfactory glomerular map and explore the potential mechanism of how this map is formed. UMass Chan Medical School UMass Molecular Medicine nature.com/articles/s4159…

Huge congratulations to graduate student, I-Hao Wang, on the publication of his second paper (and first, first author paper) from the laboratory! nature.com/articles/s4159… 1/n

Pedro A.F. Galante 🧬🚴🇧🇷: 8,000 fixed retrogene copies in human genome. ~ half show evidence of transcription in 1+ tissue (often brain, testis), at least 1/3 seem translated (ribo-seq). A subset (hundreds) are polymorphic among humans. retrogenes often overlooked in genome biology #DNASRC22

FINALLY!!! Single cell transcriptomics reveals dysregulated cellular and molecular networks in a fragile X syndrome model Elisa Manuel Garber GarberLab journals.plos.org/plosgenetics/a…

Donnard & Shu et al show how the loss of Fragile X syndrome gene FMRP affects the intricate interactions between different brain cell types Elisa Manuel Garber GarberLab @UmassMedbioinfo UMass Molecular Medicine #FragileX #InMice #Genetics #neurons doi.org/10.1371/journa…

Published today! We found that cancer cells adapting to drug treatments don't simply switch from a sensitive to resistant state; instead there's a ‘resistance continuum’ of resistant phenotypes with epigenetically reprogrammed states. 🧵⬇️ nature.com/articles/s4158… @Gustavo_SFranca

Are you a Master's student with excellent CV in cancer bioinformatics who is about to defend or recently defended? Would like to do a PhD in the Nordics on cancer network modeling? I have an opportunity with tight deadline. Email your CV and motivation: med.uio.no/ncmm/english/p…

Very excited that our paper is now online! cell.com/cell/fulltext/… Long thread on our findings on the other app 🦋