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State of the Art Review, via The BMJ Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management 🧑🏽‍⚕️🔬📈 bmj.com/content/380/bm…

We found that cellular senescence is elevated in #scleroderma skin! AND the senescence signature correlates significantly with the extracellular matrix score🧐〽️🤔 Journal of Investigative Dermatology U-M Department of Internal Medicine Michigan Research Dr. Dinesh Khanna sciencedirect.com/science/articl…

New APS Program Update that includes news & achievements, new patient education material created by Drs. Jacqueline Madison & Jason S Knight on #APS & blood clot risk, clinical study opportunities & What I’m Reading in APS Research by Dr. Ajay Tambralli: conta.cc/3NgAwxA

Congratulations to Dr. Michelle Kahlenberg who was selected as the Department of Internal Medicine Vice Chair for Basic and Translational Research, effective June 1, 2023. #GoBlue!

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Excited to share our #scleroderma work Nature Communications U-M Department of Internal Medicine nature.com/articles/s4146… Michelle Kahlenberg Eliza PS Tsou Important insights into Hippo pathway as a therapeutic target using systems biology.

Thrilled to share our latest publication that uncovers the significant role of the Hippo pathway in the progression of #scleroderma fibrosis and EndoMT via next-generation sequencing Nature Communications U-M Department of Internal Medicine Dr. Dinesh Khanna Michelle Kahlenberg #GoBlue nature.com/articles/s4146…

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Gurrea‐Rubio et al. showed prolonged survival of SCID mice bearing s.c. human breast or prostate tumors that were infused intratumorally with human lymphocytes and treated with the IgG1 mAb UMCD6, specific for human CD6 [...] bit.ly/3HXy4ID Mikel Gurrea-Rubio  U-M Department of Internal Medicine

The Hippo pathway gives new insights into #scleroderma U-M Department of Internal Medicine Dr. Dinesh Khanna

🎉 The most recent Stanford global survey of top scientists identified six faculty members from the U-M Health Rheumatology Division who ranked in the top 2% of most cited from over 10 million scientists active worldwide. Congratulations to our rheumatology faculty members!

So incredibly grateful for the support from the LEO Foundation for our research on endothelial senescence in #scleroderma! U-M Department of Internal Medicine Dr. Dinesh Khanna

We are #hiring! My lab at U-M Department of Internal Medicine has an opening for a distinguished post-doc position: careers.umich.edu/job_detail/247…. Join us to explore the world of vascular biology in #scleroderma 🤓〽️

〽️🧐 Ajay Tambralli wrote about neutrophil metabolism as a potential treatment target in thromboinflammatory diseases like APS Journal of Clinical Investigation Lyssiotis Lab Amr Sawalha, MD U-M Department of Internal Medicine Neutrophil glucose flux as a therapeutic target in antiphospholipid syndrome jci.org/articles/view/…

So incredibly grateful for the support from the LEO Foundation! U-M Department of Internal Medicine

Just published: our work showing that soluble CD13 and its receptor bradykinin receptor 1 play key roles in #scleroderma fibrosis and promote myofibroblast transformation. Dr. Dinesh Khanna U-M Department of Internal Medicine

Check out our newest study published in JCI Insight that made the cover! U-M Department of Internal Medicine Michigan Medicine U-M Medical School Research Jason S Knight

Lung inflammation seen in COVID-19 patients contains the same proteins found in multiple rheumatic diseases, according to U-M Health rheumatologists. The connection opens opportunities for treatment of inflammation experienced in severe COVID-19 cases: michmed.org/5GG2W