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Excellent cryo-CLEM/FIBSEM work by Bettina_Zens and @SchurLab! In the pursuit of maximizing the visual experience for all, a mesmerizing endeavor unfolded, involving the exploration of a dazzling array of 13 distinct cryoprotectant/buffer combinations!

Wonderful symposium! Many thanks to the organizers!

My team IGBMC is looking for a postdoc to work on the development of labels for cryo correlative light and electron microscopy (cryo-CLEM). Please find the details here igbmc.fr/en/recherche/t… and forward this message to potential candidates.

Thank you very much for the beautiful gift!

A new study by Silvia Caballero Heisenberg Lab ISTAustria & colleagues, published in Nature Physics, shows how sea squirt oocytes harness friction forces within various compartments in their interior to undergo developmental changes after conception.

1/6: #CryoEM Exhausted with fighting the air-water interface (AWI) problem during sample grid plunge freezing? We may have an easy solution for you! Read our latest preprint on how we use LEA proteins as AWI sample protectants for challenging samples: biorxiv.org/content/10.110…

Further evidence of high-resolution capabilities at 100 keV with a side-entry cryo holder using the Gatan Microscopy Alpine detector. It even performed better than the K3 on a small sample - Great collab with colleagues in Verba lab UC San Francisco biorxiv.org/cgi/content/sh…

The visualization of ribosome biogenesis is truly impressive and a testament to the wonders of modern science and the complex beauty of cellular processes.

Our team IGBMC is looking for a postdoc with expertise in cryo-EM/ET to help us explore the cytoskeleton of the specimen shown below and reveal how it transports large-scale cargo over long distances. For more information and to apply, check: igbmc.fr/en/recherche/t…

Congratulations on the wonderful work on the effect of usnic acid on ribosome biogenesis!

Very excited that my first paper found its home in Nature Communications, where we show that usnic acid inhibits the nucleolar pre-60S biogenesis in yeast. Here the link to the full publication: nature.com/articles/s4146….

Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳 Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria!  biorxiv.org/content/10.110…

Hey #teamtomo!Our 1st❄️🔬work Human Technopole is finally out!🥳nature.com/articles/s4159… Serialized On-grid Lift-In Sectioning for Tomography(SOLIST) enables a biopsy at the nanoscale and high-res❄️STA from🧍‍♀️organoids and🐭liver, brain and heart tissue!Thread by Gaia Perone below!

First short article on the CZII CryoET Data Portal: nature.com/articles/s4159… Comments/feedback welcome.

This week the 7th Austrian Cryo-EM Symposium happened & we were thrilled to once again welcome so many participants on our campus! Many thanks to the organizers IMP, Vienna BioCenter Core Facilities (VBCF) and ISTAustria for a great event! #viennabiocenter

Find our fresh peer-reviewed report on “Molecular Architecture of Synaptic Vesicles” here: pnas.org/doi/10.1073/pn… We analyzed synaptic vesicles in neurons and in isolation to describe molecules on their surface. 🧠💥🔬

Interesting in learning to process cryo-ET data in the latest version of Warp? I'll be running a workshop on April 22nd in central London, UK details+registration: forms.gle/u4Hk73jhenMvpN… Hope to see you there!

Excited to share our new preprint "Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons" biorxiv.org/content/10.110… We combine optogenetic stimulation of neurons with in situ cryo-ET to characterize membrane dynamics during vesicle fusion ❄️🔬⏱️

The John Briggs, alongside teams from CIID_Heidelberg and YaleMicroPath, uncover the elusive role of the #HIV-1 component SP2. Detailed 3D views of virus particles by #cryoEM show how SP2 helps the virus matrix to mature. ❕Read the paper nature: nature.com/articles/s4158…

Our #cryoEM technology group with scientists from the MPI of Biophysics and Vienna BioCenter, used #cryoET to capture retrotransposons in action, resolving copia in #fruitflies at sub-nanometer resolution inside cells. ❕Publication Cell: cell.com/cell/fulltext/…