The addition of FAIMS increases targeted proteomics sensitivity from FFPE tumor biopsies | buff.ly/3plehJJ #proteomics

a while ago I had looked at the issues of multi-batch #TMT. Isotopic impurities (+1Da) was an important effect that created distortions in quant, spec. for high abundance peptides. To minimise those here is an updated suggested channel layout. #proteomics

Read our mQACC recommendations for QA and QC reporting in untargeted metabolic phenotyping published today as #openaccess paper in @Metabolomics link.springer.com/article/10.100…

Single-Cell Proteomics Literature List Just reached 50 single-cell proteomics peer reviewed articles published on Orbitrap technology. Download the complete list. #singlecellproteomics #Orbitrap ow.ly/KpoS50KumF7

Fantastic collaboration with Prof. Tholey's group @ CAU on a new workflow for top-down proteomics! 🇩🇪 is very far away from 🇯🇵 but we had such great teamwork. Many thanks to Andreas sensei and @PhilippKaulich !!! pubs.acs.org/doi/10.1021/ac…

#TeamMassSpec Involved in the proteomics part of a paper and got an editor's comment, "do you consider Western blots as supp. material"? Sounds like it cannot be???!!!

I am so happy that the iSPI library, a tool for phosphoproteomics research, came out in Nature Methods today! Thanks to all the wonderful scientists who helped make this possible! Ed Huttlin Gygi Lab @HarvardCellBio Cell Signaling Technology

ANZSMS and PMV are holding a combined afternoon event on Tuesday 15th. It's FREE!!!! Check out some great talks including international guest Michael Marty showing some exciting new intact membrane protein analysis. The AGM and drinks will follow thanks to Thermo Scientific

Check out our latest publication at Proteomics! In this long-awaited study, Anders Anders H. Kverneland et al. unlock plasma proteomics using extracellular vesicles in simple and scalable workflow. Biomarker discovery research will be deeply changed. …iencejournals.onlinelibrary.wiley.com/doi/10.1002/pm…

Implementing the MSFragger Search Engine as a Node in Proteome Discoverer | buff.ly/3W04BCS #proteomics

Hybrid-DIA: Intelligent Data Acquisition for Simultaneous Targeted and Discovery Phosphoproteomics in Single Spheroids | buff.ly/3hGjv2u #proteomics

Exciting way to finish the year! It is an absolutely great example of collaborative efforts – guided by LIPID MAPS, supported by EpiLipidNET and importantly by all the software developers who contributed! bit.ly/3WA99zX - Lipidomics Tool Guide is here, check it out!

Light-regulated TurboID, or LOV-Turbo, is a feat of engineered allostery, created by Songyi Lee and Joleen Cheah via structure-guided design, then optimized by yeast display directed evolution. Activity is nearly undetectable in the dark state, but biorxiv.org/cgi/content/sh…

EPURISp: Combining Enzymatic Digestion, Ultrafiltration, and Rapid In Situ Sample Purification for High-performance Proteomics pubs.acs.org/doi/10.1021/ac… --- #proteomics #prot-paper

Happy to share our development in spatial proteomics to address the challenges of commercial LCM/LMD systems in terms of spatial resolution, throughput, and reliability. We were inspired by elegant work by Kermit Murray lab in DUV LA pubs.acs.org/doi/10.1021/ac…

Free to read in JASMS: our high-speed extraction trap, responsible for the high sensitivity of the #OrbitapAstral MS. pubs.acs.org/doi/full/10.10…

Did you ever wonder about how every parameter during phospho-enrichment affect your results? In our latest preprint we systematically analyzed almost every parameter, from beads amount to sequential enrichment. We even have data on the Astral MS!

New #OrbitrapAstral publication: taking a very deep dive into the workings of the Astral analyzer. sciencedirect.com/science/articl…

We are hiring two Research Fellows! 😁 (Spatial/SCP) and a general expert (qual/quant). $85-136k+17% Super (aka 401k). >13 mass specs, inc astral, cellenONE, robots, autobots, repeating pipettes inc tips. An amazing team 🥳 linkedin.com/jobs/view/3986… #proteomics #massspec

Data-Independent Acquisition Mass Spectrometry as a Tool for Metaproteomics: Interlaboratory Comparison Using a Model Microbiome biorxiv.org/content/10.110… --- #proteomics #prot-preprint