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People still talking generally about seed oils as though they're all one thing - they commonly vary in their omega 6, omega 3 and omega 9 content. Even oils with the same name (eg safflower) have high n6 and high no (high-oleic) varieties. Some seed oils (eg palm kernel) are

This is cool… Ketogenesis is dispensable for the metabolic adaptations to caloric restriction biorxiv.org/content/10.110…

For almost exactly 20 years, one of our kids has gone off to spend the day at a school here in SF. Today is the last day

Atul Butte died yesterday. The world lost a giant. A big bear of a man. With a huge smile. With love for everyone. With energy that could power a room. I loved everything about Atul. I loved how he was always happy. I loved how excited he was about science and helping people.

Holy shit I had no idea. RIP Atul Butte

I’ve been on this site for almost 16 years and for many, if not most of them, I’ve posted quite a bit about Ruthie and what it’s been like to raise a kid with a disability. I’ve been pretty quiet lately, but yesterday, she graduated from high school and was selected to give one

Nice to see this being shared broadly

Attn!

A must-read in the field of cardiovascular prevention: “Residual cardiovascular risk beyond LDL-C: inflammation, remnant cholesterol, and lipoprotein(a)” by Anders Wulff and Prof. Børge Nordestgaard, just published in the European Heart Journal (2025). This editorial

This is long and complicated but so important. Being persuasive does not = being honest

As a CEO, the day to day work and mission (patients, team) is really rewarding and what drives so many of us. With that said, I sometimes see colleagues lose sight of the fact that we need to deliver what we promised to shareholders. What you told them you would do as close as

🎙️ Episode 1 is LIVE! Why is eating well so hard – even when we want to? Neuroscientist Stephan J. Guyenet breaks down: 🏪 Why our food environment outpaced our biology 🧠 How certain foods hijack our brains 💊 What the data shows about Ozempic & GLP-1 drugs Apple:

We have a second drug… as I tell people, they are both my babies, but this one is especially near and dear…

Many moons ago, Kevin Hall and I talked about a book we both wished existed. No fads, no weight loss hacks—just the nutrition and metabolism science. I’m thrilled to announce that we wrote it! Out September 23 Avery Books & available now for pre-order. penguinrandomhouse.com/books/671334/f…

I’m excited to announce my new book FOOD INTELLIGENCE coauthored with brilliant journalist Julia Belluz! Cutting through the confusion about diet & health, #FoodIntelligence describes the fascinating science of how food both nourishes and harms us. penguinrandomhouse.com/books/671334/f…

Health Insurers Are Denying More Drug Claims, Data Shows - cameo by Warris Bokhari, MD nytimes.com/2025/07/18/hea…