🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Forbes published an article on an interview with Prof. Shinya Yamanaka. You can read it at the link below. #iPSC forbes.com/sites/juergene…

The tower has caught the rocket!!

"Current medicine tries to address diseases one by one, but since #aging is the major risk factor, an alternative could be to focus our attention on aging itself. This could alleviate or delay the appearance of many age-related diseases." Dr Juan Carlos Izpisua Belmonte, founding

The SMR Portal paper is now online. nature.com/articles/s4159…

🧬Thrilled to share our new preprint on predicting scRNAseq after perturbations! We benchmarked 9 models (including foundation models) across 17 datasets with 24 metrics. Check out: biorxiv.org/content/10.110…. in short: Foundation model is at least better than linear baeline

📊 many models capture global expression well but struggle with subtle gene-specific effects—or vice versa. Foundation models often outperform simpler methods but tend to converge on population averages, missing heterogeneous responses. Performance are highly contaxt specific.

🔍None of the models truly excelled in zero-shot settings. Our study calls for refining single-cell foundation models to better handle diverse perturbations. this work is done by a group of awsome people: Lanxiang Yue YOU Wenyu Xiaodong(Ethan) Liu Jiaming Kong Shuangjia Zheng

Led by Fei Gu 顾斐 and Xiaodong(Ethan) Liu, we developed a multi-omic foundation model, CREformer, for zero-shot predictions in epigenetics. New therapeutic targets are identified and validated. We thank george church and Luyi Tian 田鲁亦 for suggestion and evaluation. biorxiv.org/content/10.110…

Introducing CREformer, a multiomic foundation model pretrained on massive bulk and single-cell datasets (DNA, RNA and epigenetics). Zero-shot predictions of master regulators, cell differentiation etc. Great collboration with Alibaba DAMO Fei Gu 顾斐 george church and Xiaodong(Ethan) Liu !

Incredible work! A study years in the making published in nature. I’ve been waiting for this one. Engineered heart muscle patches from hiPSC improve cardiac function in non-human primates…and are stable in a human patient! Wow! ❤️

🚀 Update: We completed the acquisition of Biotheus. This strengthens our capabilities to develop, manufacture and commercialize next-gen bispecific antibodies, including BNT327 (PD-L1xVEGF-A bispecific), and supports the global execution of our oncology strategy.

Had a great conversation with Craig and Thomas on Discover Your Star! We discussed how cells adopt and change identity, the challenges of reprogramming, and the twists and turns of scientific discovery that shape new ideas.

gsMap paper online. Source code: github.com/JianYang-Lab/g…. Results visualisation website: yanglab.westlake.edu.cn/gsmap.

👋 Meet our new Scientific Head — Professor Jose Polo! A world leader in epigenetics & stem cell biology, Prof Polo (South Australian immunoGENomics Cancer Institute, Uni of Adelaide, Monash Medicine, Nursing and Health Sciences) brings his expertise & passion for advancing life sciences in Aus & beyond. 🌏 emblaustralia.org/jose-polo-scie…

Congratulations to Professor Jose Polo on his appointment as the new Scientific Head of EMBL Australia! Jose leads South Australian immunoGENomics Cancer Institute's Cancer Epigenetics program and is Director of the Adelaide Centre for Epigenetics Uni of Adelaide. 📢👏

Learned a lot working with Jonas (josch1@bsky) Fabian Theis @dominik1klein Daniil Bobrovskiy Treutlein lab on CellFlow: generative single-cell phenotype modeling with flow matching. Virtual protocol screening is particularly innovative! #organoids Institute of Human Biology Helmholtz Munich | @HelmholtzMunich ETH Zürich

🏃‍♂️🎉 Ready, set, RUN! 🎉🏃‍♀️ To celebrate the grand opening of Phase 3 of Westlake University’s Yungu Campus, we kicked things off last night with a fun run! Starting from the South Gate’s main square, we ran across the scenic bridges of the water ring, passed the brand-new rec

🌟Congratulations to Azim Surani Gurdon Institute Cambridge University for receiving the 2025 Kyoto Prize - Basic Sciences. Azim's research fundamentally advanced our understanding of developmental biology🔬🧬 gurdon.cam.ac.uk/kyoto-prize-wi… #KyotoPrize #AzimSurani #DevelopmentalBiology

Congratulations to Enrique and Youngsun, and gratitude to our wonderful collaborators Testicular somatic and germ cell maturation during rhesus macaque development | PNAS pnas.org/doi/10.1073/pn…

Faculty Positions in AI for Life Sciences at Westlake University nature.com/naturecareers/…