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Check out our latest work on the exploration of photocatalytic chemistry in spatiotemporal proteomics application. Bioorthogonal Photocatalytic Decaging-Enabled Mitochondrial Proteomics pubs.acs.org/doi/10.1021/ja…

Check out our latest work on "Bioorthogonally Activatable Base Editing for On-Demand Pyroptosis"😜 pubs.acs.org/doi/10.1021/ja…

Photocatalytic Chemical Crosslinking for Profiling RNA‐Protein Interactions in Living Cells onlinelibrary.wiley.com/doi/10.1002/an… Another photocatalytic chemical tool development for living cell study.

Photocatalytic Chemical Crosslinking for Profiling RNA-Protein Interactions in Living Cells (Chen) Peking University onlinelibrary.wiley.com/doi/10.1002/an…

Deciphering Life Sciences with “Live” Chemistry—The 2022 Nobel Prize in Chemistry The Nobel Prize #clickchemistry #bioorthogonal #Chemistry link.springer.com/article/10.100…

Proximity Chemistry in Living Systems bit.ly/3K8ry2i #chemistry #openaccess #science #chemtwitter

Quickest submission experience ever, 16 days in total from first submission to online publish 😃😃 …mistry-europe.onlinelibrary.wiley.com/share/5AQ5JRQW…

Optical Control of Protein Functions via Genetically Encoded Photocaged Aspartic Acids J. Am. Chem. Soc. Top Science #Chemistry #chemed #scicomm #news #Technology #Tech #NewsBreak #research #science #AcademicTwitter pubs.acs.org/doi/10.1021/ja…

Near Infrared Light-Triggered Photocatalytic Decaging for Remote-Controlled Spatiotemporal Activation in Living Mice (Xinyuan Fan and co-workers) Xinyuan Fan onlinelibrary.wiley.com/doi/10.1002/an…

Really enjoyed this collaboration with Peng and Shixian Lin on the bioorthogonal tryptophan decaging. Another exciting application of the bioorthogonal chemistry on protein activation. rdcu.be/dzUAj

Decaging-to-labeling: Development and investigation of quinone methide... sciencedirect.com/science/articl…

Bioorthogonal photocatalysis-enabled proximity labeling for primary samples. We started this direction since 2019, and now are very happy to see its great capability in solving the problems of primary proteomics. Nature Communications nature.com/articles/s4146…

I found a guy who goes around the US asking 70 to 100-year-olds their: • Biggest Regrets • Biggest Lessons • Advice to their younger self Oddly enough, most of their answers are the same… Here are my top 8:

Thanks to the chemical tubability of quinone methide labeling radius, our photocatalytic proximity labeling tools now cover intracellular (CAT-Prox, 2021), cell membrane (CAT-Ex, 2022) and intercellular spaces (CAT-Cell, 2024). pubs.acs.org/doi/10.1021/ja…

Have you read 'Dual role tertiary amines in photocatalytic cyclizations: towards sustainable syntheses of 1,3-dinitrogen heterocycles' by Fuhu Guo, Junli Zhu & Xinyuan Fan? Included in 2024 Emerging Investigators buff.ly/3TyMKnz

In situ lysosomal proteomics enabled by bioorthogonal photocatalytic proximity labelling bit.ly/40Z7YxJ

Our latest work on the photocatalytic proximity labelling: lysosomal proteomics nature.com/articles/s4192…

CAT-Tissue: Deep-Red and Ultrafast Photocatalytic Proximity Labeling Empowered In Situ Dissection of Tumor-Immune Interactions in Primary Tissues ACS Publications J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…