Monday 3 June, PRESENTATION ID C24.6 Effect of parental autoimmune diseases on type 1 diabetes in offspring can be partially explained by HLA and non-HLA polymorphisms: a nationwide registry and biobank study in 7.2M Finns Feiyi Wang

Feiyi Wang presenting our work on how autoimmune diseases cluster in families and transmission of genetic effects for T1D in families check preprint: medrxiv.org/content/10.110…

New out in Nature!! With age, women can lose one X chromosome in their leukocytes. What’s the cause/consequence? How does it differ from the loss of the Y chromosome in men? nature.com/articles/s4158… Broad Institute FinnGen FIMM HelsinkiUni National Cancer Institute Cambridge University

We use FinRegistry (8,000+ features) + deep-learning to predict 1-year mortality for the entire Finnish population (AUC=0.95)! Derive a powerful digital marker of aging And show predictions are subject to geographical and socio-economic unfairness

Family members share quite a lot genetically and environmentally. Curious about how we quantify the resemblance using any possible genealogy-traceable relatives to study human phenotypes?Join us at Exhibit hall Board 4118w to explore our latest work! 😀 #ASHG24

Why do children with Type 1 Diabetes (T1D) often have parents with autoimmune diseases? Our new study shows parental autoimmune conditions affect offspring’s T1D risk through complex genetic factors, including both HLA and non-HLA variants. 🔗 cell.com/cell-genomics/…

Many diseases run in families, including autoimmune diseases❗️ 👪👨‍👩‍👧👨‍👩‍👧‍👧 Our work - led by PhD student Feiyi Wang, co-supervised by me (Aoxing Liu), Andrea ganna, Tiinamaija Tuomi - studied the transmission of parental autoimmune diseases on T1D in offspring. We designed several

We are presenting tomorrow in Milan at #ESHG #ESHG2025 session C02 GWAS: Bigger, faster, stronger (10:30 am Auditorium) 💁‍♀️ Come and catch me if you can 🤫

Did you know that some genetic males have plasma proteomes similar to those of genetic females and vice versa? What are the consequences of this? Come discuss with me at our poster number P18.021.D on Monday 26.5. at 4pm-5pm at #ESHG2025